1069-79-0
1,2-distearoyl-sn-glycero-3-phospho-ethanolamine
CAS: 1069-79-0
Molecular Formula: C41H82NO8P
1069-79-0 - Names and Identifiers
| Name | 1,2-distearoyl-sn-glycero-3-phospho-ethanolamine |
| Synonyms | DSPE L-BETA,GAMMA-DISTEAROYL-ALPHA-CEPHALIN L-A-phosphatidylethanolamine,distearoyl L-A-PHOSPHATIDYLETHANOLAMINE,DISTEAROYL 1,2-Distearoyl-sn-glycero-3-phosphoethan L-ALPHA-PHOSPHATIDYLETHANOLAMINE, DISTEAROYL 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine 1,2-distearoyl-sn-glycero-3-phospho-ethanolamine 1,2-DIOCTADECANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE (R)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]ethane-1,2-diyl distearate 3-{[(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(octadecanoyloxy)propyl octadecanoate (2R)-3-{[(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(octadecanoyloxy)propyl octadecanoate |
| CAS | 1069-79-0 |
| EINECS | 213-963-9 |
| InChI | InChI=1/C41H82NO8P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-40(43)47-37-39(38-49-51(45,46)48-36-35-42)50-41(44)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h39H,3-38,42H2,1-2H3,(H,45,46)/t39-/m1/s1 |
1069-79-0 - Physico-chemical Properties
| Molecular Formula | C41H82NO8P |
| Molar Mass | 748.07 |
| Density | 0.996 |
| Melting Point | 172-173℃ |
| Boling Point | 760.2±70.0 °C(Predicted) |
| Flash Point | 413.5°C |
| Solubility | Chloroform (Slightly, Heated, Sonicated) |
| Vapor Presure | 2.68E-25mmHg at 25°C |
| Appearance | White to white-like powder |
| Color | White to Off-White |
| BRN | 1730641 |
| pKa | 1.17±0.50(Predicted) |
| Storage Condition | -20°C |
| Refractive Index | 1.473 |
| MDL | MFCD00036777 |
| In vitro study | 1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine (DSPE), one of many phosphoethanolamine (PE) lipids, cannot sustain a lamellar form at pH values below ∼8.5, the pKa of the ethanolamine moiety. |
1069-79-0 - Risk and Safety
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 10-21 |
| HS Code | 29232000 |
1069-79-0 - Reference Information
| Use | 1, 2-distearoyl-SN-glycerol -3-phosphorylethanolamine is also called 1, 2-stearoyl-SN-propyltriol-3-phosphatidylethanolamine, which can be used to prepare glycosylated phosphatidylethanolamine (Amadoriphosphatidylethanolamine,Amadori-PE), glycosylated phosphatidylethanolamine is a kind of substance produced by the reaction of aldehydes and ketone groups of compounds such as phosphatidylethanolamine and reducing sugars in food or organisms. |
| toxicity | glycosylated phosphatidylethanolamine is a potential chemical hazard. A large number of animal and clinical experiments have shown that glycosylated lipids are closely related to the onset of diabetes complications, aging sexual dysfunction, cancer and other diseases. |
| Biological activity | 1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine (DSPE) is a phosphatidic acid ethanolamine (PE) lipid, which can be used to synthesize liposomes. |
Last Update：2024-04-09 02:00:05
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