1072944-18-3
2-Fluoro-4-methylpyridine-5-boronicacid
CAS: 1072944-18-3
Molecular Formula: C6H7BFNO2
1072944-18-3 - Names and Identifiers
1072944-18-3 - Physico-chemical Properties
| Molecular Formula | C6H7BFNO2 |
| Molar Mass | 154.93 |
| Density | 1.28±0.1 g/cm3(Predicted) |
| Boling Point | 331.6±52.0 °C(Predicted) |
| Flash Point | 154.359 °C |
| pKa | 7.05±0.58(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| MDL | MFCD08741406 |
1072944-18-3 - Introduction
2-Fluoro-4-methylpyridine-5-boronic acid, also known as 2-fluoro-4-methylpyridine-5-borate (FMPB), is an organoboron compound. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: Colorless crystalline solid.
-Solubility: Soluble in many organic solvents, such as dimethyl sulfoxide, dimethylformamide, etc.
-Stability: relatively stable at room temperature.
Use:
-Catalyst: As a boron-containing catalyst, it is used in organic synthesis reactions, such as C- C bond formation, C- N bond formation, etc.
-Fluorescent probe: Due to its fluorescent properties, it can be used as a fluorescent probe agent for biological detection and imaging.
Preparation Method:
The preparation of-2-fluoro-4-methylpyridine-5-boronic acid can be completed by a two-step reaction.
-The first step is to condense 2-fluoro-4-methylpyridine with trimethylboronic acid to produce an intermediate.
-The second step is to react the intermediate with boronic acid or other boronic acid derivatives to obtain the product.
Safety Information:
-2-Fluoro-4-methylpyridine-5-boronic acid is a chemical and should follow appropriate safety procedures.
-Wear appropriate personal protective equipment such as gloves, goggles, and lab coats during use and handling.
-avoid contact with skin, eyes, respiratory tract, such as accidental contact, please immediately rinse with plenty of water.
-During storage and use, keep a well-ventilated environment to avoid fire and static electricity.
-When disposing of waste, it needs to be properly disposed of in accordance with local regulations.
Nature:
-Appearance: Colorless crystalline solid.
-Solubility: Soluble in many organic solvents, such as dimethyl sulfoxide, dimethylformamide, etc.
-Stability: relatively stable at room temperature.
Use:
-Catalyst: As a boron-containing catalyst, it is used in organic synthesis reactions, such as C- C bond formation, C- N bond formation, etc.
-Fluorescent probe: Due to its fluorescent properties, it can be used as a fluorescent probe agent for biological detection and imaging.
Preparation Method:
The preparation of-2-fluoro-4-methylpyridine-5-boronic acid can be completed by a two-step reaction.
-The first step is to condense 2-fluoro-4-methylpyridine with trimethylboronic acid to produce an intermediate.
-The second step is to react the intermediate with boronic acid or other boronic acid derivatives to obtain the product.
Safety Information:
-2-Fluoro-4-methylpyridine-5-boronic acid is a chemical and should follow appropriate safety procedures.
-Wear appropriate personal protective equipment such as gloves, goggles, and lab coats during use and handling.
-avoid contact with skin, eyes, respiratory tract, such as accidental contact, please immediately rinse with plenty of water.
-During storage and use, keep a well-ventilated environment to avoid fire and static electricity.
-When disposing of waste, it needs to be properly disposed of in accordance with local regulations.
Last Update：2024-04-09 21:04:16
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