1072951-50-8
2-Hydroxy-4-trifluoromethylphenylboronic acid
CAS: 1072951-50-8
Molecular Formula: C7H6BF3O3
1072951-50-8 - Names and Identifiers
1072951-50-8 - Physico-chemical Properties
| Molecular Formula | C7H6BF3O3 |
| Molar Mass | 205.93 |
| Density | 1.50±0.1 g/cm3(Predicted) |
| Boling Point | 317.2±52.0 °C(Predicted) |
| pKa | 7.90±0.58(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
1072951-50-8 - Reference Information
| Uses | 2-hydroxy-4-trifluoromethylphenylboronic acid is an organic intermediate, and alkyl boronic acid compounds are a class of important organic synthesis intermediates. It can be cross-coupled with electrophiles to prepare drug molecules and play an important role in medicinal chemistry applications. |
| Application Example | 2-hydroxy-4-trifluoromethylphenylboronic acid can be used to prepare compounds having the following structure for the treatment and/or prevention of neurodegenerative diseases (e. g., neurodegeneration in prion diseases (priondisease)). These compounds are used to treat diseases, conditions or disorders that are at least partially mediated by eukaryotic initiation factor 2B, such as Parkinson's disease (PD), amyotrophic lateral sclerosis (ALS), Alzheimer's disease (AD) and frontotemporal dementia (FTD) and other neurodegenerative diseases have a negative impact on the lives of millions of people. |
Last Update：2024-04-10 22:29:15
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