1072951-51-9
3,4-Bis(methoxycarbonyl)phenylboronic acid
CAS: 1072951-51-9
Molecular Formula: C10H11BO6
1072951-51-9 - Names and Identifiers
1072951-51-9 - Physico-chemical Properties
| Molecular Formula | C10H11BO6 |
| Molar Mass | 238 |
| Storage Condition | Inert atmosphere,Room Temperature |
| Sensitive | Irritant |
| MDL | MFCD11504854 |
1072951-51-9 - Introduction
3,4-Bis (methoxycarbonyl) phenylboronic acid is an organoboron compound. The following is a description of its nature, use, preparation and safety information:
Nature:
1. Chemical formula: C12H12B2O6
2. Appearance: colorless crystal or white powder
3. Solubility: Soluble in most organic solvents, such as ethanol, dimethylformamide and dichloromethane
4. Melting point: about 140-141°C
5. Main structural characteristics: There are two methoxycarbonyl groups (COOMe) and a benzene ring in the molecule, and two hydroxyl groups (OH) are connected to the B atom on the benzene ring
Use:
1. Catalyst: 3,4-bis (methoxycarbonyl) phenylboronic acid can be used as a catalyst in organic synthesis, for example, for C- C bond formation reaction, oxidation reaction and cyclization reaction.
2. Drug synthesis: It is also commonly used in the field of drug synthesis to prepare biologically active molecules.
Preparation Method:
The preparation method of 3,4-bis (methoxycarbonyl) phenylboronic acid generally includes the following steps:
1. phenylboronic acid and boron trioxide are reacted in an appropriate organic solvent to generate borate ester.
2. Add excess methanol and heat to reflux for reaction.
3. After completion of the reaction, the solvent and the remaining boron trioxide are distilled off to obtain the target product.
Safety Information:
1.3, 4-Bis (methoxycarbonyl) phenylboronic acid is an organic compound that requires care to prevent inhalation, swallowing, or contact with skin and eyes.
2. in handling and handling, should wear appropriate protective gloves, glasses and clothing.
3. It should be used in a well-ventilated place and away from fire and heat sources.
4. If skin or eye contact occurs, rinse immediately with plenty of water and seek medical help.
5. During use and storage, it should be separated from other chemicals and properly sealed.
Nature:
1. Chemical formula: C12H12B2O6
2. Appearance: colorless crystal or white powder
3. Solubility: Soluble in most organic solvents, such as ethanol, dimethylformamide and dichloromethane
4. Melting point: about 140-141°C
5. Main structural characteristics: There are two methoxycarbonyl groups (COOMe) and a benzene ring in the molecule, and two hydroxyl groups (OH) are connected to the B atom on the benzene ring
Use:
1. Catalyst: 3,4-bis (methoxycarbonyl) phenylboronic acid can be used as a catalyst in organic synthesis, for example, for C- C bond formation reaction, oxidation reaction and cyclization reaction.
2. Drug synthesis: It is also commonly used in the field of drug synthesis to prepare biologically active molecules.
Preparation Method:
The preparation method of 3,4-bis (methoxycarbonyl) phenylboronic acid generally includes the following steps:
1. phenylboronic acid and boron trioxide are reacted in an appropriate organic solvent to generate borate ester.
2. Add excess methanol and heat to reflux for reaction.
3. After completion of the reaction, the solvent and the remaining boron trioxide are distilled off to obtain the target product.
Safety Information:
1.3, 4-Bis (methoxycarbonyl) phenylboronic acid is an organic compound that requires care to prevent inhalation, swallowing, or contact with skin and eyes.
2. in handling and handling, should wear appropriate protective gloves, glasses and clothing.
3. It should be used in a well-ventilated place and away from fire and heat sources.
4. If skin or eye contact occurs, rinse immediately with plenty of water and seek medical help.
5. During use and storage, it should be separated from other chemicals and properly sealed.
Last Update：2024-04-09 19:05:44
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Product Name: 3,4-BIS(METHOXYCARBONYL)PHENYLBORONIC ACID Visit Supplier Webpage Request for quotationCAS: 1072951-51-9
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
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Spot supply
Product Name: (3,4-Bis(methoxycarbonyl)phenyl)boronic acid Request for quotationCAS: 1072951-51-9
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: (3,4-Bis(methoxycarbonyl)phenyl)boronic acid Visit Supplier Webpage Request for quotationCAS: 1072951-51-9
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
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View History
1072951-51-9
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