1073312-28-3

1073312-28-3 - Names and Identifiers

Name	2-Chloro-3-fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
Synonyms	2-Chloro-3-fluoropyridyl-5-boronic acid pinacol ester 6-Chloro-5-fluoropyridine-3-boronic acid pinacol ester 2-CHLORO-3-FLUOROPYRIDINE-5-BORONIC ACID PINACOL ESTER (6-CHLORO-5-FLUOROPYRIDIN-3-YL)BORONIC ACID PINACOL ESTER 2-Chloro-3-fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine 2-Chloro-3-fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-pyridine Pyridine, 2-chloro-3-fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
CAS	1073312-28-3
InChI	InChI=1S/C11H14BClFNO2/c1-10(2)11(3,4)17-12(16-10)7-5-8(14)9(13)15-6-7/h5-6H,1-4H3

1073312-28-3 - Physico-chemical Properties

Molecular Formula	C11H14BClFNO2
Molar Mass	257.5
Density	1.2±0.1 g/cm3
Boling Point	323.7±42.0 °C at 760 mmHg
Flash Point	149.6±27.9 °C
Vapor Presure	0.0±0.7 mmHg at 25°C
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.493

1073312-28-3 - Introduction

6-Chloro-5-fluoropyridine-3-boronic acid pinacol ester is an organic compound with the chemical formula C9H6BClFNO2. The following is its nature, use, preparation and safety information:

Nature:
-Appearance: White solid
-Melting point: approximately 120-122°C
-Solubility: Soluble in organic solvents such as methanol and ether

Use:
-6-Chloro-5-fluoropyridine-3-boronic acid pinacol ester is an important organic synthesis intermediate, mainly used in the preparation of other drugs, pesticides and chemicals.

Preparation Method:
-6-Chloro-5-fluoropyridine-3-boronic acid pinacol ester can be generated by the reaction of pyridine with fluorophenyl magnesium chloride (Grignard reagent), and then reacted with trimethoxyborane.

Safety Information:
-The specific safety data of 6-chloro-5-fluoropyridine-3-boronic acid pinacol ester may vary by supplier and batch, so the product manual and safety should be read carefully before use Data sheet.
-It may cause irritation and allergic reactions to the human body, so pay attention to avoid contact with skin, eyes and respiratory tract when using it.
-Follow laboratory safety practices during operation, ensure good ventilation conditions, and wear appropriate protective equipment, such as laboratory gloves, goggles and protective masks.
-If accidentally splashed into the eyes or skin, rinse immediately with plenty of water for at least 15 minutes and seek medical help.
-This compound may be toxic to aquatic organisms and should be avoided in water and soil. Dispose of waste before use.

Last Update：2024-04-09 20:49:11

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