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107724-20-9

eplerenone

CAS: 107724-20-9

Molecular Formula: C24H30O6

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107724-20-9 - Names and Identifiers

Name eplerenone
Synonyms plerenone
HSDB 7522
eplerenone
the intermediates
Eplerenone [USAN]
Eplerenone for system suitability
Eplerenone intermediate Eplerenone
pregn-4-ene-7,21-dicarboxylic acid 9,11-epoxy-17-hydroxy-3-oxo gamma-lactone methyl ester
(7α,11α,17α)-9,11-epoxy-17-hydroxy-3-oxo-γ-lactone-pregn-4-ene-7,21-dicarboxylic acid-7-methyl ester
Pregn-4-ene-7,21-dicarboxylic acid, 9,11-epoxy-17-hydroxy-3-oxo-, gamma-lactone, methyl ester, (7alpha,11alpha,17alpha)-
methyl (4aS,4bR,6aS,7R,9aS,10R)-4a,6a-dimethyl-2,5'-dioxo-2,4,4',4a,5',5a,6,6a,8,9,9a,9b,10,11-tetradecahydro-3H,3'H-spiro[cyclopenta[7,8]phenanthro[4b,5-b]oxirene-7,2'-furan]-10-carboxylate
methyl (4aS,4bR,5aS,6aS,7R,9aS,9bR,10R)-4a,6a-dimethyl-2,5'-dioxo-2,4,4',4a,5',5a,6,6a,8,9,9a,9b,10,11-tetradecahydro-3H,3'H-spiro[cyclopenta[7,8]phenanthro[4b,5-b]oxirene-7,2'-furan]-10-carboxylate
methyl (4aS,4bR,5aR,6aS,7R,9aS,9bR,10R)-4a,6a-dimethyl-2,5'-dioxo-2,4,4',4a,5',5a,6,6a,8,9,9a,9b,10,11-tetradecahydro-3H,3'H-spiro[cyclopenta[7,8]phenanthro[4b,5-b]oxirene-7,2'-furan]-10-carboxylate
methyl (4aS,4bR,5aR,6aS,7S,9aS,9bR,10R)-4a,6a-dimethyl-2,5'-dioxo-2,4,4',4a,5',5a,6,6a,8,9,9a,9b,10,11-tetradecahydro-3H,3'H-spiro[cyclopenta[7,8]phenanthro[4b,5-b]oxirene-7,2'-furan]-10-carboxylate
(2'R,4aS,4bR,5aR,6aS,9aS,9bR,10R)-Methyl 4a,6a-diMethyl-2,4'-dioxo-3,4,4a,4',5a,5',6,6a,8,9,9a,9b,10,11-tetradecahydro-2H,3'H-spiro[cyclopenta[1,2]phenanthro[4,4a-b]oxirene-7,2'-furan]-10-carboxylate
CAS 107724-20-9
EINECS 600-850-8
InChI InChI=1/C24H30O6/c1-21-7-4-14(25)10-13(21)11-15(20(27)28-3)19-16-5-8-23(9-6-18(26)30-23)22(16,2)12-17-24(19,21)29-17/h10,15-17,19H,4-9,11-12H2,1-3H3/t15-,16+,17-,19+,21+,22+,23-,24-/m1/s1
InChIKey UZZAHAKTLYRDOK-MGIDJNSKSA-N

107724-20-9 - Physico-chemical Properties

Molecular FormulaC24H30O6
Molar Mass414.49
Density1.31±0.1 g/cm3(Predicted)
Melting Point241-243°C
Boling Point597.9±50.0 °C(Predicted)
Specific Rotation(α)D +5° (c = 0.437 in chloroform)
Flash Point259.474°C
Solubility DMSO: soluble2mg/mL, clear (warmed)
Vapor Presure0mmHg at 25°C
AppearanceWhite solid
Colorwhite to beige
Maximum wavelength(λmax)['240nm(lit.)']
Merck14,3625
Storage ConditionStore at RT
Refractive Index1.587
UseCardiotonic drugs

107724-20-9 - Risk and Safety

UN IDs3077
WGK Germany3
HS Code29322090

107724-20-9 - Nature

Open Data Verified Data

white or off-white crystalline powder, tasteless. mp240 ~ 242 ℃. [a]D 50(c-0.437 chloroform). UV absorption maximum 240nm (e16800). Very slightly soluble in water, its solubility depends on the pH value. Its partition coefficient in octanol/water was 7.1 at pH-7.0.

Last Update：2025-06-10 22:55:16

107724-20-9 - Application

Open Data Verified Data

A selective aldosterone inhibitor. New drugs for the treatment of hypertension and other cardiovascular diseases. For the treatment of high blood pressure.

Last Update：2025-08-19 16:24:40
107724-20-9
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Shanghai Macklin Biochemical Co., Ltd
Featured ProductsSpot supply
Product Name: Eplerenone Visit Supplier Webpage Request for quotation
CAS: 107724-20-9
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
Suzhou Haofan biological Co., Ltd.
Featured Products
Product Name: Eplerenone Request for quotation
CAS: 107724-20-9
Tel: +86 0512-69209928
Email: wuhao@highfine.com
　　　　 merry@highfine.com
　　　　 chenmengqi@highfine.com
QQ: 4006286883 Click to send a QQ message
Shanghai Amole Biotechnology Co., Ltd.
Spot supply
Product Name: Eplerenone Request for quotation
CAS: 107724-20-9
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365 Click to send a QQ message
Wechat: 18916960931
SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: Eplerenone Visit Supplier Webpage Request for quotation
CAS: 107724-20-9
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922 Click to send a QQ message
Wechat: 18621343501
WhatsApp: +86-18621343501
MedChemExpress (MCE)
Multiple SpecificationsSpot supply
Product Name: Epoxymexrenone (Standard) Visit Supplier Webpage Request for quotation
CAS: 107724-20-9
Tel: 609-228-6898
Email: sales@medchemexpress.com
　　　　 tech@medchemexpress.com
Mobile: 609-228-6898
BOC Sciences
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Product Name: Eplerenone Visit Supplier Webpage Request for quotation
CAS: 107724-20-9
Tel: +16314854226
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Mobile: +16314854226
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SKYRUN INDUSTRIAL CO.,LTD
Spot supply
Product Name: Eplerenone Visit Supplier Webpage Request for quotation
CAS: 107724-20-9
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185 Click to send a QQ messageSend QQ message
Wechat: chinaskyrun
Hefei TNJ Chemical Industry Co.,Ltd.
Product Name: eplerenone Request for quotation
CAS: 107724-20-9
Tel: 0086-551-65418684
Email: sales@tnjchem.com
　　　　 info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840 Click to send a QQ message
Wechat: 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
Shanghai Yuanye Bio-Technology Co., Ltd.
Multiple SpecificationsSpot supply
Product Name: Eplerenone Visit Supplier Webpage Request for quotation
CAS: 107724-20-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
Zhejiang Xianju Junye Pharmaceutical Co., Ltd
Product Name: Eplerenone Request for quotation
CAS: 107724-20-9
Tel: 0576-87821302
Email: yashon313@gmail.com
Mobile: 15168672352
QQ: 16155972 Click to send a QQ messageSend QQ message
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107724-20-9
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