1082843-72-8
6-bromo-3-chloropyrazin-2-amine
CAS: 1082843-72-8
Molecular Formula: C4H3BrClN3
1082843-72-8 - Names and Identifiers
| Name | 6-bromo-3-chloropyrazin-2-amine |
| Synonyms | 6-Bromo-3-chloropyrazin-2-amine 6-Bromo-3-chloro-2-pyrazinamine 6-bromo-3-chloropyrazin-2-amine 2-Amino-3-chloro-6-bromopyrazine 2-Amino-6-bromo-3-chloropyrazine 3-Chloro-6-bromopyrazin-2-ylamine 2-Pyrazinamine, 6-bromo-3-chloro- |
| CAS | 1082843-72-8 |
| EINECS | 604-604-1 |
| InChI | InChI=1S/C4H3BrClN3/c5-2-1-8-3(6)4(7)9-2/h1H,(H2,7,9) |
1082843-72-8 - Physico-chemical Properties
| Molecular Formula | C4H3BrClN3 |
| Molar Mass | 208.44 |
| Density | 1.960 |
| Boling Point | 288℃ |
| Flash Point | 128℃ |
| pKa | 0.05±0.10(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
| Sensitive | Irritant |
| MDL | MFCD13193368 |
1082843-72-8 - Introduction
3-Chloro-6-bromopyrazin-2-amine is a chemical compound whose molecular formula is C7H4BrClN4. The following is a description of the properties, uses, preparation and safety information of this compound:
Properties: 3-Chloro-6-bromopyrazin-2-amine is a white crystalline solid with high thermal stability. It is almost insoluble in water at normal temperature, but soluble in organic solvents such as methanol, ethanol and dimethyl sulfoxide.
Purpose: 3-Chloro-6-bromopyrazin-2-amine is commonly used as a pharmaceutical intermediate, especially in the synthesis of antiepileptic drugs. In addition, it can also be used in the synthesis of other organic compounds, such as halogenated pyrazine derivatives.
Preparation method: The preparation method of 3-chloro-6-bromopyrazin-2-amine is usually obtained by reacting 6-bromopyrazin-2-amine with aluminum trichloride under the catalysis of cuprous chloride. The specific synthesis process can be carried out by the technology of laboratory organic synthesis.
Safety Information: Pay attention to safety when handling 3-chloro-6-bromopyrazin-2-amine. It is an organic compound with certain toxicity and irritation, so personal protective equipment such as protective gloves, safety glasses and laboratory coats should be worn during operation. In addition, the safe handling of chemicals should be strictly observed during storage and handling, avoid contact with skin and eyes, and ensure that they are transported and stored in a well-ventilated place. If any accident or discomfort occurs, medical help should be sought immediately and detailed information about the compound should be provided.
Properties: 3-Chloro-6-bromopyrazin-2-amine is a white crystalline solid with high thermal stability. It is almost insoluble in water at normal temperature, but soluble in organic solvents such as methanol, ethanol and dimethyl sulfoxide.
Purpose: 3-Chloro-6-bromopyrazin-2-amine is commonly used as a pharmaceutical intermediate, especially in the synthesis of antiepileptic drugs. In addition, it can also be used in the synthesis of other organic compounds, such as halogenated pyrazine derivatives.
Preparation method: The preparation method of 3-chloro-6-bromopyrazin-2-amine is usually obtained by reacting 6-bromopyrazin-2-amine with aluminum trichloride under the catalysis of cuprous chloride. The specific synthesis process can be carried out by the technology of laboratory organic synthesis.
Safety Information: Pay attention to safety when handling 3-chloro-6-bromopyrazin-2-amine. It is an organic compound with certain toxicity and irritation, so personal protective equipment such as protective gloves, safety glasses and laboratory coats should be worn during operation. In addition, the safe handling of chemicals should be strictly observed during storage and handling, avoid contact with skin and eyes, and ensure that they are transported and stored in a well-ventilated place. If any accident or discomfort occurs, medical help should be sought immediately and detailed information about the compound should be provided.
Last Update：2024-04-09 20:52:54
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