108433-99-4
Magainin I
CAS: 108433-99-4
Molecular Formula: C112H177N29O28S
108433-99-4 - Names and Identifiers
108433-99-4 - Physico-chemical Properties
| Molecular Formula | C112H177N29O28S |
| Molar Mass | 2409.85 |
| Density | 1.268±0.06 g/cm3(Predicted) |
| Boling Point | 2396.1±65.0 °C(Predicted) |
| Storage Condition | −20°C |
| MDL | MFCD00133521 |
| In vitro study | Magainin 1 interacts with acidic lipids through electrostatic interactions followed by hydrophobic interactions to form an amphiphilic helix, inducing the leakage. Magainin 1 induces the leakage of calcein specifically out of negatively-charged vesicles. The peptide binds to bovine brain phosphatidylserine sonicated vesicles according to the Langmuir isotherm with a binding constant of 3.8×10 5 M-1 and a binding-site number of 0.10 per lipid molecule. |
108433-99-4 - Risk and Safety
| WGK Germany | 3 |
108433-99-4 - Reference Information
| biological activity | Magainin 1 (Magainin I) is an antibacterial and amphiphilic peptide isolated from Xenopus laevis skin. Magainin 1 showed antibiotic activity against a variety of Gram-negative and Gram-positive bacteria. |
| in vitro study | Magainin 1 interacts with acidic lips through electrostatic interactions followed by hydrophobic interactions to form an amphiphilic helix, inducing the leakage. Magainin 1 induces the leakage of calcein specifically out of negatively-charged vesicles. The peptide binds to bovine brain phosphatidylserine sonicated vesicles according to the Langmuir isotherm with a binding constant of 3.8 × 10 5 M-1 and a binding-site number of 0.10 per lipid molecule. |
Last Update：2024-04-09 20:52:54
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