1094484-55-5
1H-Pyrazole-4-carboxaldehyde,3-(difluoromethyl)-1-methyl-
CAS: 1094484-55-5
Molecular Formula: C6H6F2N2O
1094484-55-5 - Names and Identifiers
1094484-55-5 - Physico-chemical Properties
| Molecular Formula | C6H6F2N2O |
| Molar Mass | 160.12 |
| Storage Condition | 2-8℃ |
1094484-55-5 - Introduction
4-Aldo-3-(difluoromethyl)-1-methyl -1H-pyrazole is an organic compound with the chemical formula C7H4F2N2O. It is a white crystalline solid, slightly soluble in water and soluble in organic solvents. It has a density of 1.37g/cm³ and a melting point of 76-78°C.
This compound has certain biological activity and is commonly used as a pesticide and pharmaceutical intermediate. It is widely used in the pharmaceutical industry to synthesize various fluorine-containing organic compounds, such as antiviral drugs and anti-cancer drugs.
there are many ways to prepare 4-aldehyde -3-(difluoromethyl)-1-methyl -1H-pyrazole, the common ones are as follows:
1. react 2-amino -5-fluorobenzoic acid with hydrofluoric acid, and then react with thionyl chloride to obtain 4-amino -3-fluorobenzoic acid. The 4-amino -3-fluorobenzoic acid was converted into acid chloride, and then Mannich with formaldehyde under acid catalysis to obtain the target product.
In terms of safety information, because this compound contains fluorine atoms, fluorine compounds often have a certain degree of toxicity. During the operation, attention should be paid to comply with the relevant safety procedures and wear appropriate personal protective equipment. Avoid contact with skin and eyes, and avoid inhaling its vapors. If contact occurs, rinse immediately with plenty of water and seek medical treatment.
This compound has certain biological activity and is commonly used as a pesticide and pharmaceutical intermediate. It is widely used in the pharmaceutical industry to synthesize various fluorine-containing organic compounds, such as antiviral drugs and anti-cancer drugs.
there are many ways to prepare 4-aldehyde -3-(difluoromethyl)-1-methyl -1H-pyrazole, the common ones are as follows:
1. react 2-amino -5-fluorobenzoic acid with hydrofluoric acid, and then react with thionyl chloride to obtain 4-amino -3-fluorobenzoic acid. The 4-amino -3-fluorobenzoic acid was converted into acid chloride, and then Mannich with formaldehyde under acid catalysis to obtain the target product.
In terms of safety information, because this compound contains fluorine atoms, fluorine compounds often have a certain degree of toxicity. During the operation, attention should be paid to comply with the relevant safety procedures and wear appropriate personal protective equipment. Avoid contact with skin and eyes, and avoid inhaling its vapors. If contact occurs, rinse immediately with plenty of water and seek medical treatment.
Last Update：2024-04-09 21:04:16
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Product Name: 3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carbaldehyde Visit Supplier Webpage Request for quotationCAS: 1094484-55-5
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Product Name: 4-Formyl-3-(trifluoromethyl)-1-methyl-1H-pyrazole Visit Supplier Webpage Request for quotation
CAS: 1094484-55-5
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CAS: 1094484-55-5
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View History
1094484-55-5
12178-06-2
103-53-7
Aluminum chlorideoxide
铼酸
1-PYRROLIDINAMINE
Magnesium peroxide complex
路通
2-(methylthio)pyrazine
126-87-4
12178-06-2
103-53-7
Aluminum chlorideoxide
铼酸
1-PYRROLIDINAMINE
Magnesium peroxide complex
路通
2-(methylthio)pyrazine
126-87-4