1111638-02-8
5-Bromo-2-methyl-7-azaindole
CAS: 1111638-02-8
Molecular Formula: C8H7BrN2
1111638-02-8 - Names and Identifiers
| Name | 5-Bromo-2-methyl-7-azaindole |
| Synonyms | 5-Bromo-2-methyl-7-Azaind... 5-Bromo-2-methyl-7-Azaindole 5-Bromo-2-methyl-7-azaindole 5-Bromo-2-iodo-1H-pyrrolo[2,3-b]pyridine 5-Bromo-2-methyl-1H-pyrrolo[2,3-b]pyridine 1H-Pyrrolo[2,3-b]pyridine, 5-broMo-2-Methyl- 1H-pyrrolo[2,3-b]pyridine, 5-bromo-2-methyl- |
| CAS | 1111638-02-8 |
| InChI | InChI=1S/C8H7BrN2/c1-5-2-6-3-7(9)4-10-8(6)11-5/h2-4H,1H3,(H,10,11) |
1111638-02-8 - Physico-chemical Properties
| Molecular Formula | C8H7BrN2 |
| Molar Mass | 211.06 |
| Density | 1.654 |
| Boling Point | 320.567 °C at 760 mmHg |
| Flash Point | 147.674 °C |
| pKa | 13.49±0.40(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
1111638-02-8 - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R22 - Harmful if swallowed R41 - Risk of serious damage to eyes |
| WGK Germany | 3 |
| Hazard Class | IRRITANT |
1111638-02-8 - Introduction
5-Bromo-2-methyl-7-azaindole (abbreviated as Br-Me-N7) is an organic compound with the following properties:
1. Appearance: The Br-Me-N7 is a colorless or pale yellow crystalline solid.
2. melting point: about 50-52 degrees Celsius.
3. Solubility: Br-Me-N7 can be dissolved in some organic solvents, such as methanol, acetonitrile and dichloromethane.
4. Stability: The Br-Me-N7 has good thermal stability and is relatively stable under conventional experimental conditions.
The main use of Br-Me-N7 is as an intermediate in organic synthesis. It can be further synthesized by chemical reactions with other compounds. For example, it can be used as an inhibitor of electron transfer enzymes for drug research and development.
The method of preparing the Br-Me-N7 may employ a multi-step reaction. A common preparation method is by bromination of picoline, followed by reduction and ring-closing reaction with ammonia gas to obtain Br-Me-N7.
Regarding safety information, Br-Me-N7 are less toxic, but still need to be properly managed and used in the laboratory. Use personal protective equipment during handling and storage and avoid contact with skin and eyes. At the same time, it should be stored in a sealed container and away from fire and oxidizing agents. In use, should comply with the relevant safety procedures and regulations. It should be noted that the use and disposal of Br-Me-N7 should comply with local laws and regulations.
1. Appearance: The Br-Me-N7 is a colorless or pale yellow crystalline solid.
2. melting point: about 50-52 degrees Celsius.
3. Solubility: Br-Me-N7 can be dissolved in some organic solvents, such as methanol, acetonitrile and dichloromethane.
4. Stability: The Br-Me-N7 has good thermal stability and is relatively stable under conventional experimental conditions.
The main use of Br-Me-N7 is as an intermediate in organic synthesis. It can be further synthesized by chemical reactions with other compounds. For example, it can be used as an inhibitor of electron transfer enzymes for drug research and development.
The method of preparing the Br-Me-N7 may employ a multi-step reaction. A common preparation method is by bromination of picoline, followed by reduction and ring-closing reaction with ammonia gas to obtain Br-Me-N7.
Regarding safety information, Br-Me-N7 are less toxic, but still need to be properly managed and used in the laboratory. Use personal protective equipment during handling and storage and avoid contact with skin and eyes. At the same time, it should be stored in a sealed container and away from fire and oxidizing agents. In use, should comply with the relevant safety procedures and regulations. It should be noted that the use and disposal of Br-Me-N7 should comply with local laws and regulations.
Last Update：2024-04-09 21:11:58
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