1116339-62-8

1116339-62-8 - Names and Identifiers

Name	6-fluoro-4-(trifluoromethyl)quinoline-2-carbohydrazide
Synonyms	6-Fluoro-4-(trifluoromethyl)-2-quinolinecarbohydrazide 6-fluoro-4-(trifluoromethyl)quinoline-2-carbohydrazide 6-Fluoro-4-(trifluoromethyl)quinoline-2-carbohydrazide 2-Quinolinecarboxylic acid, 6-fluoro-4-(trifluoromethyl)-, hydrazide
CAS	1116339-62-8
InChI	InChI=1S/C11H7F4N3O/c12-5-1-2-8-6(3-5)7(11(13,14)15)4-9(17-8)10(19)18-16/h1-4H,16H2,(H,18,19)

1116339-62-8 - Physico-chemical Properties

Molecular Formula	C11H7F4N3O
Molar Mass	273.19
Storage Condition	2-8°C
Sensitive	IRRITANT
MDL	MFCD11046314

1116339-62-8 - Risk and Safety

Risk Codes	R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
HS Code	29334900

1116339-62-8 - Introduction

6-Fluoro-4-trifluoromethylquinoline-2-carbohydrazide is an organic compound. The following is a detailed description of its nature, use, formulation and safety information:

Nature:
-Chemical formula: C8H3F4N3O
-Molecular weight: 235.12g/mol
-Appearance: Colorless crystalline solid
-Melting point: 140-142 degrees Celsius
-Boiling point: 390 degrees Celsius
-Solubility: Soluble in water, soluble in organic solvents such as ethanol and dichloromethane

Use:
6-Fluoro-4-trifluoromethylquinoline-2-carbohydrazide is mainly used in pesticide synthesis, especially as an intermediate of pyrethroid insecticides. Such compounds can be prepared by modifying known synthetic methods.

Preparation Method:
The preparation method of 6-fluoro-4-trifluoromethylquinoline -2-carboxylic acid hydrazide is as follows:
1. First, 4-trifluoromethylquinolin-2-one is reacted with ammonia water to generate 4-trifluoromethylquinolin-2-amine.
2. Then, 4-trifluoromethylquinolin-2-amine is reacted with fluoroacetyl hydrazide to generate 6-fluoro-4-trifluoromethylquinoline-2-carbohydrazide under alkaline conditions.

Safety Information:
6-Fluoro-4-trifluoromethylquinoline-2-carbohydrazide should be handled with caution during preparation and use, because it may have certain toxicity. When using, should follow the relevant safety procedures, avoid direct contact with skin, eyes and respiratory tract. At the same time, the compound should be stored properly, away from ignition and oxidizing agents. Waste generated during disposal shall also be disposed of in accordance with relevant regulations. If the compound is accidentally exposed or inhaled, seek medical attention immediately and provide the appropriate safety data sheet.

Last Update：2024-04-10 22:29:15