113886-70-7
2'-(O-METHYL)-5-METHYLCYTIDINE
CAS: 113886-70-7
Molecular Formula: C11H17N3O5
113886-70-7 - Names and Identifiers
113886-70-7 - Physico-chemical Properties
| Molecular Formula | C11H17N3O5 |
| Molar Mass | 271.27 |
| Density | 1.61±0.1 g/cm3(Predicted) |
| Melting Point | 235-238°C |
| Boling Point | 504.6±60.0 °C(Predicted) |
| Solubility | DMSO (Slightly), Water (Slightly, Sonicated) |
| Appearance | Solid |
| Color | White to Off-White |
| pKa | 13.37±0.70(Predicted) |
| Storage Condition | Refrigerator |
113886-70-7 - Introduction
5-Methyl -2 '-oxymethylcytidine is an organic compound with the chemical formula C11H15N3O6, which is a methylated and oxymethylated cytidine derivative.
Nature:
5-methyl -2 '-oxymethyl cytidine is a solid powder, stable at room temperature. It is white or almost white crystalline and has good solubility. It dissolves easily in water and is stable at neutral pH. Like other cytidine, 5-methyl -2 '-oxymethylcytidine is susceptible to hydrolysis under acidic conditions.
Use:
5-Methyl -2 '-oxomethylcytidine is commonly used in pharmaceutical research and biochemistry. It has antiviral activity, especially for hepatitis B virus and herpes virus B has a good inhibitory effect. It is also used as a precursor compound for the synthesis of nucleoside analogs and improved drugs.
Method:
The preparation of 5-methyl -2 '-oxymethylcytidine is generally accomplished by chemical synthesis. A common preparation method is to first react cytidine with a methylating agent to obtain 5-methylcytidine, and then react with an oxymethylating agent to obtain the target product 5-methyl -2 '-oxymethylcytidine.
Safety Information:
5-Methyl-2 '-oxomethylcytidine has limited toxicity data and safety information. However, according to the study of related cytidine analogs, it may have some toxicity to the human body. Appropriate protective measures shall be taken during handling and storage to avoid direct contact with skin, eyes and inhalation of dust. In the use of the process should pay attention to control risks, and follow the relevant safety procedures.
Nature:
5-methyl -2 '-oxymethyl cytidine is a solid powder, stable at room temperature. It is white or almost white crystalline and has good solubility. It dissolves easily in water and is stable at neutral pH. Like other cytidine, 5-methyl -2 '-oxymethylcytidine is susceptible to hydrolysis under acidic conditions.
Use:
5-Methyl -2 '-oxomethylcytidine is commonly used in pharmaceutical research and biochemistry. It has antiviral activity, especially for hepatitis B virus and herpes virus B has a good inhibitory effect. It is also used as a precursor compound for the synthesis of nucleoside analogs and improved drugs.
Method:
The preparation of 5-methyl -2 '-oxymethylcytidine is generally accomplished by chemical synthesis. A common preparation method is to first react cytidine with a methylating agent to obtain 5-methylcytidine, and then react with an oxymethylating agent to obtain the target product 5-methyl -2 '-oxymethylcytidine.
Safety Information:
5-Methyl-2 '-oxomethylcytidine has limited toxicity data and safety information. However, according to the study of related cytidine analogs, it may have some toxicity to the human body. Appropriate protective measures shall be taken during handling and storage to avoid direct contact with skin, eyes and inhalation of dust. In the use of the process should pay attention to control risks, and follow the relevant safety procedures.
Last Update：2024-04-09 02:00:41
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