113886-71-8
Cytidine,N-acetyl-2'-O-methyl-
CAS: 113886-71-8
Molecular Formula: C12H17N3O6
113886-71-8 - Names and Identifiers
113886-71-8 - Physico-chemical Properties
| Molecular Formula | C12H17N3O6 |
| Molar Mass | 299.28 |
| Density | 1.58±0.1 g/cm3(Predicted) |
| Solubility | Aqueous Base (Slightly), DMSO (Slightly), Methanol (Slightly, Heated, Sonicated) |
| Appearance | Solid |
| Color | White to Off-White |
| pKa | 10.20±0.20(Predicted) |
| Storage Condition | -20°C Freezer, Under inert atmosphere |
113886-71-8 - Introduction
N4-Acetyl-2 '-methoxycytidine (abbreviated as N4-EtAcG) is a compound with certain properties and uses. The following is a description of its nature, use, preparation and safety information:
Nature:
N4-EtAcG is an organic compound with a chemical formula of C15H20N4O6 and a molecular weight of 360.34g/mol. It is a white to slightly yellow solid. It is easily soluble in solvents, but has low solubility in water. In addition, it is stable under conventional chemical and physical conditions.
Use:
N4-EtAcG are primarily used in biotechnology research and pharmaceuticals. It is a compound with important biological activity and can be used as an intermediate for antiviral and anticancer drugs. In research, it has also been used as a nucleotide fluorescent labeling reagent, a tool for RNA modification studies, and gene expression analysis.
Method:
The preparation method of N4-EtAcG is relatively complicated, and the basic steps are as follows:
1. First, N-acetytidine (N-AcG) was synthesized through a series of steps.
2. A methoxy (CH3O) functional group was introduced into the N-AcG to give 2 '-methoxy-N-acetytidine (2'-MeO-N-AcG).
3. Finally, by reacting with acetic anhydride, the acetyl group is introduced into the N4 position to obtain N4-EtAcG.
Safety Information:
There are few specific reports on the toxicity and safety of N4-EtAcG. However, as a chemical compound, personal protective measures should be taken when using it. In the process of operation and preparation, it is necessary to follow the laboratory safety procedures. In addition, the reasonable storage and handling of the compound, pay attention to prevent its contact with fire sources, oxidants, etc., to avoid accidents. If further safety information is required, it is recommended to consult the relevant literature or contact a professional body.
Nature:
N4-EtAcG is an organic compound with a chemical formula of C15H20N4O6 and a molecular weight of 360.34g/mol. It is a white to slightly yellow solid. It is easily soluble in solvents, but has low solubility in water. In addition, it is stable under conventional chemical and physical conditions.
Use:
N4-EtAcG are primarily used in biotechnology research and pharmaceuticals. It is a compound with important biological activity and can be used as an intermediate for antiviral and anticancer drugs. In research, it has also been used as a nucleotide fluorescent labeling reagent, a tool for RNA modification studies, and gene expression analysis.
Method:
The preparation method of N4-EtAcG is relatively complicated, and the basic steps are as follows:
1. First, N-acetytidine (N-AcG) was synthesized through a series of steps.
2. A methoxy (CH3O) functional group was introduced into the N-AcG to give 2 '-methoxy-N-acetytidine (2'-MeO-N-AcG).
3. Finally, by reacting with acetic anhydride, the acetyl group is introduced into the N4 position to obtain N4-EtAcG.
Safety Information:
There are few specific reports on the toxicity and safety of N4-EtAcG. However, as a chemical compound, personal protective measures should be taken when using it. In the process of operation and preparation, it is necessary to follow the laboratory safety procedures. In addition, the reasonable storage and handling of the compound, pay attention to prevent its contact with fire sources, oxidants, etc., to avoid accidents. If further safety information is required, it is recommended to consult the relevant literature or contact a professional body.
Last Update：2024-04-09 21:54:55
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