1143459-81-7
N-(2-methyl-5-nitrophenyl)-4(pyridin-3-yl)thiazol-2-amine
CAS: 1143459-81-7
Molecular Formula: C15H12N4O2S.HBr
1143459-81-7 - Names and Identifiers
1143459-81-7 - Physico-chemical Properties
| Molecular Formula | C15H12N4O2S.HBr |
| Molar Mass | 393.25832 |
1143459-81-7 - Introduction
N-(2-methyl-5-nitrophenyl)-4-(3-pyridyl)-2-thiazolamine hydrobromide is a complex organic compound. The following is a description of some of the properties, uses, preparation and safety information of the compound:
Nature:
N-(2-methyl-5-nitrophenyl)-4-(3-pyridyl)-2-thiazolamine hydrobromide is usually yellow crystals and can be dissolved in some organic solvents, such as methanol and ethanol. It is relatively stable in air, but may decompose when exposed to high temperatures and light.
Use:
The compound is often used as a pharmaceutical intermediate in the field of medicine. It has certain applications in the synthesis of anti-tumor drugs, antiviral drugs, antibacterial drugs and so on.
Method:
The preparation method of N-(2-methyl-5-nitrophenyl)-4-(3-pyridyl)-2-thiazolamine hydrobromide generally includes the following steps: firstly, 2-methyl -5-nitroaniline is synthesized as a starting material; 2-Methyl-5-nitroaniline is then reacted with 3-pyridinaldehyde under appropriate conditions to give N-(2-methyl-5-nitrophenyl)-3-pyridinecarboxaldehyde; finally, N-(2-methyl-5-nitrophenyl)-3-pyridinecarboxaldehyde is reacted with 2-mercapto-4-aminothiazole to give the final product.
Safety Information:
The safety of N-(2-methyl-5-nitrophenyl)-4-(3-pyridyl)-2-thiazolamine hydrobromide has not been fully evaluated. Therefore, care should be taken to prevent contact with skin, eyes and inhalation during use. Appropriate protective measures, such as gloves, goggles and respiratory protection, should be taken. At the same time, the compound should be stored in a dry, cool place, away from fire and oxidizing agents. Local regulations and safe practices need to be observed during handling and disposal.
Nature:
N-(2-methyl-5-nitrophenyl)-4-(3-pyridyl)-2-thiazolamine hydrobromide is usually yellow crystals and can be dissolved in some organic solvents, such as methanol and ethanol. It is relatively stable in air, but may decompose when exposed to high temperatures and light.
Use:
The compound is often used as a pharmaceutical intermediate in the field of medicine. It has certain applications in the synthesis of anti-tumor drugs, antiviral drugs, antibacterial drugs and so on.
Method:
The preparation method of N-(2-methyl-5-nitrophenyl)-4-(3-pyridyl)-2-thiazolamine hydrobromide generally includes the following steps: firstly, 2-methyl -5-nitroaniline is synthesized as a starting material; 2-Methyl-5-nitroaniline is then reacted with 3-pyridinaldehyde under appropriate conditions to give N-(2-methyl-5-nitrophenyl)-3-pyridinecarboxaldehyde; finally, N-(2-methyl-5-nitrophenyl)-3-pyridinecarboxaldehyde is reacted with 2-mercapto-4-aminothiazole to give the final product.
Safety Information:
The safety of N-(2-methyl-5-nitrophenyl)-4-(3-pyridyl)-2-thiazolamine hydrobromide has not been fully evaluated. Therefore, care should be taken to prevent contact with skin, eyes and inhalation during use. Appropriate protective measures, such as gloves, goggles and respiratory protection, should be taken. At the same time, the compound should be stored in a dry, cool place, away from fire and oxidizing agents. Local regulations and safe practices need to be observed during handling and disposal.
Last Update：2024-04-09 21:11:58
