1152439-79-6

1152439-79-6 - Names and Identifiers

Name	Imidazo[1,5-a]pyrazin-1-amine, 5,6,7,8-tetrahydro-3-(trifluoromethyl)-
Synonyms	3-(trifluoromethyl)-5H,6H,7H,8H-imidazo[1,5-a]pyrazin-1-amine 3-(Trifluoromethyl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyrazin-1-amine 5,6,7,8-tetrahydro-3-(trifluoromethyl)-Imidazo[1,5-a]pyrazin-1-amine Imidazo[1,5-a]pyrazin-1-amine, 5,6,7,8-tetrahydro-3-(trifluoromethyl)- IMidazo[1,5-a]pyrazin-1-aMine, 5,6,7,8-tetrahydro-3-(trifluoroMethyl)-
CAS	1152439-79-6

1152439-79-6 - Physico-chemical Properties

Molecular Formula	C7H9F3N4
Molar Mass	206.17
Density	1.72±0.1 g/cm3(Predicted)
Boling Point	328.0±42.0 °C(Predicted)
pKa	8.36±0.20(Predicted)
Storage Condition	Room Temprature

1152439-79-6 - Introduction

1-Amino-3-trifluoromethyl-imidazo [1,5-a] tetrahydropyrazine, also known as AFIT, is an organic compound. The following is a brief description of its nature, use, preparation and safety information:

Nature:
1-Amino-3-trifluoromethyl-imidazo [1,5-a] tetrahydropyrazine is a solid, usually in the form of a white crystal or powder. It has low solubility and is almost insoluble in water. Its formula is C9H11F3N4. This compound is relatively stable at room temperature, but may decompose at high temperatures.

Use:
1-Amino-3-trifluoromethyl-imidazo [1,5-a] tetrahydropyrazine has a wide range of applications. It can be used as a pharmaceutical intermediate for the synthesis of various pharmaceutical compounds. In addition, AFIT can also be used as a catalyst and reducing agent in organic synthesis for the promotion and catalysis of organic reactions.

Method:
A common method for the synthesis of 1-amino-3-trifluoromethyl-imidazo [1,5-a] tetrahydropyrazine is through the dinitrobenzamide on the nitrogen of the imidazole ring structure and the trifluoro system Reaction. The reaction is usually carried out under an inert atmosphere and the dinitro compound is reduced to the corresponding 1-amino derivative by addition of a suitable reducing agent.

Safety Information:
The safety information of 1-amino-3-trifluoromethyl-imidazo [1,5-a] tetrahydropyrazine is relatively limited, so it is necessary to take appropriate precautions when using or handling this compound. It may cause irritation to the eyes, skin and respiratory tract, so appropriate personal protective measures should be taken, such as wearing goggles, protective gloves and respiratory protective equipment. At the same time, it is necessary to avoid its reaction with strong oxidants or other harmful substances to prevent accidents. During use or storage, please observe the relevant chemical safety procedures.

Last Update：2024-04-09 21:11:58