1159429-52-3
Methyl 4-(difluoroMethoxy)-3-hydroxybenzoate
CAS: 1159429-52-3
Molecular Formula: C9H8F2O4
1159429-52-3 - Names and Identifiers
1159429-52-3 - Physico-chemical Properties
| Molecular Formula | C9H8F2O4 |
| Molar Mass | 218.15 |
| Storage Condition | 2-8 ℃, stored in nitrogen |
1159429-52-3 - Introduction
Methyl 4-difluoromethoxy-3-hydroxybenzoate, also known as DFMO, is an organic compound. The following is a description of the nature, use, preparation and safety information of DFMO:
1. nature:
-Appearance: DFMO is a white crystalline solid.
-Solubility: DFMO is soluble in some organic solvents, such as dimethyl sulfoxide and chloroform.
-Melting point: The experimental melting point of DFMO is 110-112°C.
-Chemical structure: The structural formula of DFMO is CH3OC6H3(OH)COOCH2F2.
2. use:
-Drug Application: DFMO is a drug with the potential to inhibit the proliferation of a variety of tumor cells. It is used as one of the experimental treatments for primary and recurrent renal cell carcinoma, melanoma and some other types of cancer.
-Laboratory applications: DFMO is also used as a chemical reagent and biological tool in laboratory research.
3. Preparation method:
Because the synthesis of DFMO is complex and requires special reagents and conditions, it is generally prepared in the laboratory through a multi-step reaction. The specific synthesis method is complex and requires expertise and equipment in organic chemical synthesis.
4. Safety Information:
-Toxicity: The toxicity of DFMO is low, but it still needs to be used with caution. During the preparation and operation, the safe operation of the chemical laboratory should be observed.
-Protective measures: Wear personal protective equipment during use, such as laboratory gloves, goggles and laboratory clothes, to avoid contact with skin, eyes and other mucous membranes.
-Storage: DFMO should be stored in a sealed container, away from ignition and oxidizing agents.
-Waste Disposal: Disposal of DFMO and its wastes should be considered in accordance with local environmental regulations and follow relevant safe disposal procedures.
Please note that DFMO is a laboratory compound, and its application in drug therapy is still in the experimental stage. Any practical application needs to be carried out under the guidance of a doctor or professional.
1. nature:
-Appearance: DFMO is a white crystalline solid.
-Solubility: DFMO is soluble in some organic solvents, such as dimethyl sulfoxide and chloroform.
-Melting point: The experimental melting point of DFMO is 110-112°C.
-Chemical structure: The structural formula of DFMO is CH3OC6H3(OH)COOCH2F2.
2. use:
-Drug Application: DFMO is a drug with the potential to inhibit the proliferation of a variety of tumor cells. It is used as one of the experimental treatments for primary and recurrent renal cell carcinoma, melanoma and some other types of cancer.
-Laboratory applications: DFMO is also used as a chemical reagent and biological tool in laboratory research.
3. Preparation method:
Because the synthesis of DFMO is complex and requires special reagents and conditions, it is generally prepared in the laboratory through a multi-step reaction. The specific synthesis method is complex and requires expertise and equipment in organic chemical synthesis.
4. Safety Information:
-Toxicity: The toxicity of DFMO is low, but it still needs to be used with caution. During the preparation and operation, the safe operation of the chemical laboratory should be observed.
-Protective measures: Wear personal protective equipment during use, such as laboratory gloves, goggles and laboratory clothes, to avoid contact with skin, eyes and other mucous membranes.
-Storage: DFMO should be stored in a sealed container, away from ignition and oxidizing agents.
-Waste Disposal: Disposal of DFMO and its wastes should be considered in accordance with local environmental regulations and follow relevant safe disposal procedures.
Please note that DFMO is a laboratory compound, and its application in drug therapy is still in the experimental stage. Any practical application needs to be carried out under the guidance of a doctor or professional.
Last Update：2024-04-09 21:04:16
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