1162257-58-0
5-(Trifluoromethyl)pyridine-2-boronic acid
CAS: 1162257-58-0
Molecular Formula: C6H5BF3NO2
1162257-58-0 - Names and Identifiers
1162257-58-0 - Physico-chemical Properties
| Molecular Formula | C6H5BF3NO2 |
| Molar Mass | 190.92 |
| Density | 1.44 |
| Boling Point | 289.2℃ |
| Flash Point | 128.7℃ |
| pKa | 7.08±0.53(Predicted) |
| Storage Condition | Inert atmosphere,Store in freezer, under -20°C |
1162257-58-0 - Introduction
5-Trifluoromethylpyridine-2-boronic acid is an organic compound with the chemical formula CFL3 C∞H₂ N-2-B(OH). Its nature, use, formulation and safety information are described below.
Properties: 5-Trifluoromethylpyridine-2-boronic acid is a colorless solid. It has poor solubility in water, but can be well dissolved in some organic solvents. It is a weak acid that reacts easily with bases. The compound has good thermal stability and oxidation stability.
Purpose: 5-trifluoromethylpyridine-2-boronic acid is an important organic synthesis intermediate. It is widely used in organic synthesis, such as catalytic cross-coupling reaction, hydrogenation reaction and cyclization reaction. In addition, it can also be used as a raw material for organic electronic materials.
preparation method: there are many preparation methods of 5-trifluoromethylpyridine -2-boric acid, one of the commonly used methods is obtained by the reaction of trifluoromethylpyridine and boric acid. The reaction is generally carried out under an inert atmosphere.
Safety Information: According to the literature, 5-trifluoromethylpyridine-2-boronic acid has no clear toxicity and danger. However, as a chemical, it is also necessary to observe safe operating procedures and avoid contact with skin, eyes or mouth. Attention should be paid to fire prevention and ventilation during use, storage and handling.
Properties: 5-Trifluoromethylpyridine-2-boronic acid is a colorless solid. It has poor solubility in water, but can be well dissolved in some organic solvents. It is a weak acid that reacts easily with bases. The compound has good thermal stability and oxidation stability.
Purpose: 5-trifluoromethylpyridine-2-boronic acid is an important organic synthesis intermediate. It is widely used in organic synthesis, such as catalytic cross-coupling reaction, hydrogenation reaction and cyclization reaction. In addition, it can also be used as a raw material for organic electronic materials.
preparation method: there are many preparation methods of 5-trifluoromethylpyridine -2-boric acid, one of the commonly used methods is obtained by the reaction of trifluoromethylpyridine and boric acid. The reaction is generally carried out under an inert atmosphere.
Safety Information: According to the literature, 5-trifluoromethylpyridine-2-boronic acid has no clear toxicity and danger. However, as a chemical, it is also necessary to observe safe operating procedures and avoid contact with skin, eyes or mouth. Attention should be paid to fire prevention and ventilation during use, storage and handling.
Last Update：2024-04-10 22:29:15
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