117666-97-4
FMOC-D-BPA-OH
CAS: 117666-97-4
Molecular Formula: C31H25NO5
117666-97-4 - Names and Identifiers
| Name | FMOC-D-BPA-OH |
| Synonyms | FMoc-D-Bpa-OH FMOC-D-BPA-OH Fmoc-D-Phe(4-Bz)-Oh Fmoc-D-Phe(P-Bz)-Oh Fmoc-D-Phe(4-Bzo)-Oh Fmoc-P-Bz-D-Phenylalanine FMOC-D-P-BENZOYLPHENYLALANINE Fmoc-D-P-Benzoylphenylalanine Fmoc-D-4-Benzoylphenylalanine FMOC-4-BENZOYL-D-PHENYLALANINE Fmoc-4-Benzoyl-D-Phenylalanine N-Fmoc-4-benzoyl-D-phenylalanine (9H-Fluoren-9-yl)MethOxy]Carbonyl D-Bpa-OH 4-Benzoyl-NALPHA-9-fluorenylmethoxycarbonyl-D-phenylalanine N-[(9H-fluoren-9-ylmethoxy)carbonyl]-4-(phenylcarbonyl)-D-phenylalanine (R)-2-((((9H-Fluoren-9-yl)Methoxy)carbonyl)aMino)-3-(4-benzoylphenyl)propanoic acid |
| CAS | 117666-97-4 |
| InChI | InChI=1/C31H25NO5/c33-29(21-8-2-1-3-9-21)22-16-14-20(15-17-22)18-28(30(34)35)32-31(36)37-19-27-25-12-6-4-10-23(25)24-11-5-7-13-26(24)27/h1-17,27-28H,18-19H2,(H,32,36)(H,34,35)/t28-/m1/s1 |
117666-97-4 - Physico-chemical Properties
| Molecular Formula | C31H25NO5 |
| Molar Mass | 491.53 |
| Density | 1.288g/cm3 |
| Boling Point | 729°C at 760 mmHg |
| Flash Point | 394.7°C |
| Vapor Presure | 2.61E-22mmHg at 25°C |
| Appearance | Powder |
| Color | Pale brown |
| Storage Condition | 2-8°C |
| Refractive Index | 1.644 |
| Physical and Chemical Properties | Storage Conditions: 2-8 ℃ WGK Germany:3 |
117666-97-4 - Risk and Safety
| WGK Germany | 3 |
| Hazard Class | IRRITANT |
117666-97-4 - Introduction
Fmoc-4-benzoyl-D-phenylalanine is an organic compound commonly used in peptide synthesis in chemical synthesis and in pharmaceutical research. The following is a brief description of its nature, use, preparation and safety information:
Nature:
Fmoc-4-benzoyl-D-phenylalanine is a white crystalline solid, solid at room temperature, soluble in organic solvents such as dimethyl sulfoxide (DMSO) and chloroform. It is an amino acid derivative with a special ultraviolet absorption peak in the spectrum.
Use:
Fmoc-4-benzoyl-D-phenylalanine is a protecting group reagent for peptide synthesis and is commonly used in the synthesis of polypeptides and their derivatives. It protects the amino terminus of the peptide chain from undesired reactions during synthesis. The Fmoc protecting group can be easily removed at the end of the synthesis to obtain the original peptide structure.
Preparation Method:
The synthesis of Fmoc-4-benzoyl-D-phenylalanine is usually obtained by reacting D-phenylalanine with Fmoc-4-benzoic anhydride under basic conditions. After completion of the reaction, a pure product was obtained by steps of purification and crystallization.
Safety Information:
When handling Fmoc-4-benzoyl-D-phenylalanine, care should be taken to prevent contact with skin, eyes and administration. It should be operated under well-ventilated laboratory conditions and kept away from combustibles and heat sources. Local safe practices should be followed when handling and disposing of waste. Wear appropriate protective equipment such as laboratory glasses, gloves and laboratory coats during use. In case of accidental contact, rinse immediately with plenty of water and seek medical help.
Nature:
Fmoc-4-benzoyl-D-phenylalanine is a white crystalline solid, solid at room temperature, soluble in organic solvents such as dimethyl sulfoxide (DMSO) and chloroform. It is an amino acid derivative with a special ultraviolet absorption peak in the spectrum.
Use:
Fmoc-4-benzoyl-D-phenylalanine is a protecting group reagent for peptide synthesis and is commonly used in the synthesis of polypeptides and their derivatives. It protects the amino terminus of the peptide chain from undesired reactions during synthesis. The Fmoc protecting group can be easily removed at the end of the synthesis to obtain the original peptide structure.
Preparation Method:
The synthesis of Fmoc-4-benzoyl-D-phenylalanine is usually obtained by reacting D-phenylalanine with Fmoc-4-benzoic anhydride under basic conditions. After completion of the reaction, a pure product was obtained by steps of purification and crystallization.
Safety Information:
When handling Fmoc-4-benzoyl-D-phenylalanine, care should be taken to prevent contact with skin, eyes and administration. It should be operated under well-ventilated laboratory conditions and kept away from combustibles and heat sources. Local safe practices should be followed when handling and disposing of waste. Wear appropriate protective equipment such as laboratory glasses, gloves and laboratory coats during use. In case of accidental contact, rinse immediately with plenty of water and seek medical help.
Last Update：2024-04-09 15:17:51
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