1184936-21-7

1184936-21-7 - Names and Identifiers

Name	4-Chloro-2-(trifluoroacetyl)aniline Hydrochloride Hydrate
Synonyms	1-(2-Amino-5-chlorophenyl) -2,2,2-trifluoroethanone hydrochloride hydrate 4-Chloro-2-(trifluoroacetyl)aniline hydrochloride hydrate 4-Chloro-2-(trifluoroacetyl)aniline Hydrochloride Hydrate
CAS	1184936-21-7

1184936-21-7 - Physico-chemical Properties

Molecular Formula	C8H8Cl2F3NO2
Molar Mass	278.0558296
Storage Condition	2-8℃

1184936-21-7 - Introduction

4-Chloro-2-trifluoroacetylaniline hydrate hydrochloride is an organic compound with the chemical formula C8H6ClF3NO · HCl · H2O. The following are the properties, use, preparation and safety information of the compound:

Nature:
1. Appearance: white crystalline solid.
2. solubility: soluble in water and some organic solvents.
3. melting point: about 116-118 degrees Celsius.

Use:
1. pharmaceutical field: can be used as a reagent for chemical synthesis.
2. research field: can be used in organic synthesis, such as drug synthesis, pesticide synthesis.

Preparation Method:
can usually be synthesized by the following steps:
1. At low temperature, 4-chloroaniline and trifluoroacetyl chloride are reacted to obtain 4-chloro-2-trifluoroacetanilide.
2. 4-chloro-2-trifluoroacetanilide is reacted with hydrochloric acid to obtain 4-chloro-2-trifluoroacetylaniline hydrochloride.
3. Finally, 4-chloro-2-trifluoroacetylaniline hydrochloride was crystallized from water to give the hydrate hydrochloride.

Safety Information:
1. The compound is irritating and should not be in contact with skin and eyes. Wear suitable personal protective equipment during operation.
2. Good ventilation conditions should be paid attention to when operating or preparing the compound to avoid inhalation or exposure to high concentrations of gas or dust.
3. during storage, it should be placed in a dry, cool place, away from flammables and oxidants.
4. Unauthorized personnel are prohibited from using the compound, and waste and residues must be properly disposed.

Note: The above information is for reference only. Please refer to the relevant chemical literature and safety technical instructions for specific operation and use.

Last Update：2024-04-09 21:00:56