118609-38-4
Fmoc-D-Thr-OH
CAS: 118609-38-4;157355-81-2
Molecular Formula: C20H21NO5
118609-38-4 - Names and Identifiers
| Name | Fmoc-D-Thr-OH |
| Synonyms | FMOC-D-THR Fmoc-D-Thr-OH FMOC-D-THR-OH FMOC-D-THR BR FMOC-D-THREONINE n-fmoc-d-threonine N-ALPHA-FMOC-D-THREONINE FMOC-D-THREONINE extrapure n-[(9h-fluoren-9-ylmethoxy)carbonyl]-d-threonine N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-threonine N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-D-THREONINE N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-allothreonine (2R,3S)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-3-hydroxybutanoic acid |
| CAS | 118609-38-4 157355-81-2 |
| InChI | InChI=1/C19H19NO5/c1-11(21)17(18(22)23)20-19(24)25-10-16-14-8-4-2-6-12(14)13-7-3-5-9-15(13)16/h2-9,11,16-17,21H,10H2,1H3,(H,20,24)(H,22,23)/t11?,17-/m1/s1 |
118609-38-4 - Physico-chemical Properties
| Molecular Formula | C20H21NO5 |
| Molar Mass | 355.38 |
| Density | 1.308±0.06 g/cm3(Predicted) |
| Boling Point | 595.2±50.0 °C(Predicted) |
| Flash Point | 314.6°C |
| Water Solubility | Sparingly soluble in water (0.053 g/L) (25°C). |
| Vapor Presure | 4.45E-15mmHg at 25°C |
| Appearance | Solid |
| pKa | 3.49±0.10(Predicted) |
| Storage Condition | Store at RT. |
| Refractive Index | 1.617 |
| Physical and Chemical Properties | Storage Conditions: Store at RT. |
118609-38-4 - Introduction
Fmoc-D-threonine is an amino acid derivative with the following properties:
1. properties: Fmoc-D-threonine is a white crystalline solid, soluble in organic solvents such as dimethylformamide (DMF) and dichloromethane. It has an amino group and a carboxyl group, and a protecting group Fmoc (9-fluorobiphenylformyl). It is the D-isomer of threonine.
2. use: Fmoc-D-threonine is usually used in solid phase peptide synthesis, as a building block of the peptide chain. It can be used for the synthesis of biologically active peptide, protein and polypeptide drugs. Fmoc-D-threonine can also be used to study the substrate and receptor structures of enzymes.
3. preparation method: synthesis of Fmoc-D-threonine can be through the synthesis of general threonine, and then its dextrorotatory isomerization to D-form, and finally through the introduction of protecting groups to obtain Fmoc-D-threonine.
4. Safety information: Fmoc-D-threonine has low toxicity under general operating conditions. Care should be taken to avoid inhalation, ingestion or contact with skin and eyes. Appropriate personal protective equipment, such as lab gloves, safety glasses and laboratory coats, should be worn during use. In case of accidental contact or misuse, seek medical attention immediately and take the product instructions to the hospital.
1. properties: Fmoc-D-threonine is a white crystalline solid, soluble in organic solvents such as dimethylformamide (DMF) and dichloromethane. It has an amino group and a carboxyl group, and a protecting group Fmoc (9-fluorobiphenylformyl). It is the D-isomer of threonine.
2. use: Fmoc-D-threonine is usually used in solid phase peptide synthesis, as a building block of the peptide chain. It can be used for the synthesis of biologically active peptide, protein and polypeptide drugs. Fmoc-D-threonine can also be used to study the substrate and receptor structures of enzymes.
3. preparation method: synthesis of Fmoc-D-threonine can be through the synthesis of general threonine, and then its dextrorotatory isomerization to D-form, and finally through the introduction of protecting groups to obtain Fmoc-D-threonine.
4. Safety information: Fmoc-D-threonine has low toxicity under general operating conditions. Care should be taken to avoid inhalation, ingestion or contact with skin and eyes. Appropriate personal protective equipment, such as lab gloves, safety glasses and laboratory coats, should be worn during use. In case of accidental contact or misuse, seek medical attention immediately and take the product instructions to the hospital.
Last Update：2024-04-09 02:00:41
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