119-24-4
pteroic acid
CAS: 119-24-4
Molecular Formula: C14H12N6O3
119-24-4 - Names and Identifiers
| Name | pteroic acid |
| Synonyms | NSC 14972 pteroic acid Pyrofolic acid p-[(2-AMino-4-hydroxy-6-pteridylMethyl)aMino]benzoic Acid p-((2-amino-4-hydroxypteridin-6-yl)methylamino)benzoic acid 4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoic acid 4-[(2-azanyl-4-oxo-1H-pteridin-6-yl)methylamino]benzoic acid 4-[(2-amino-4-keto-1H-pteridin-6-yl)methylamino]benzoic acid 4-{[(2-Amino-4-hydroxypteridin-6-yl)methyl]amino}benzoic acid 4-[[(2-AMino-3,4-dihydro-4-oxo-6-pteridinyl)Methyl]aMino]benzoic Acid 4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}benzoic acid |
| CAS | 119-24-4 |
| EINECS | 240-718-3 |
| InChI | InChI=1/C14H12N6O3/c15-14-19-11-10(12(21)20-14)18-9(6-17-11)5-16-8-3-1-7(2-4-8)13(22)23/h1-4,6,16H,5H2,(H,22,23)(H3,15,17,19,20,21) |
119-24-4 - Physico-chemical Properties
| Molecular Formula | C14H12N6O3 |
| Molar Mass | 312.28 |
| Density | 1.69 |
| Melting Point | >400℃ |
| Boling Point | 610.0±65.0 °C(Predicted) |
| Flash Point | 352.9°C |
| Solubility | Aqueous Base (Slightly), DMSO (Slightly) |
| Vapor Presure | 2.61E-18mmHg at 25°C |
| Appearance | neat |
| Color | Light Yellow to Brown |
| pKa | 4.65±0.10(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.803 |
| Use | This product is for scientific research only and shall not be used for other purposes. |
119-24-4 - Risk and Safety
| WGK Germany | 3 |
119-24-4 - Reference Information
| Introduction | Pteranoic acid, chemical name 4-[[(2-amino -3, 4-dihydro-4-oxo-6-pteridine) methyl] amino] benzoic acid, is a pteridine derivative, pteridine is a pigment separated from the wings of butterflies, hence the name pteridine. Pteridine is composed of two rings of pyrimidine and pyrazine, and it is also a component of vitamin folic acid. Recent new drug studies have found that folic acid has a targeted effect in animals. It will guide drug molecules into designated cells, thereby playing a therapeutic role. Pterine acid is an important precursor for the synthesis of these folic acid carrier drugs. The low-price, high-quality preparation method of pterine acid is an important guarantee for the development and production of such new drugs. |
| Preparation | Pteranoic acid can be prepared by various conventional methods including synthesis, microbial degradation of folic acid, enzymatic degradation of folic acid, hydrolysis of folic acid, and other conventional methods. In general, pterenoic acid prepared by these methods can usually be contaminated with a considerable amount of folic acid. For example, pterenic acid prepared by enzymatic degradation may contain 25% folic acid. Therefore, there is a need for effective methods to remove folate contaminants and other impurities derived from the preparation of pteranoic acid. Vitamin-drug conjugates, including pterenic acid conjugates, can be prepared using synthetic methods. In some cases, those synthetic methods can also lead to the formation of by-products, impurities, or other contaminants. |
Last Update：2024-04-09 21:21:28
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View History
119-24-4
CIS 3 HEXENYL BENZOATE
Fema no. 2991
Duloxetime
Dynapen
Terasil Violet BL 01
RCS-4 M11 metabolite
dicyclopentadiene (stabilized with bht)
pennzone e
Hydrobromic Acid Hydrazine
CIS 3 HEXENYL BENZOATE
Fema no. 2991
Duloxetime
Dynapen
Terasil Violet BL 01
RCS-4 M11 metabolite
dicyclopentadiene (stabilized with bht)
pennzone e
Hydrobromic Acid Hydrazine