119020-03-0
(S)-2-(Aminomethyl)-1-Cbz-pyrrolidine
CAS: 119020-03-0
Molecular Formula: C13H18N2O2
119020-03-0 - Names and Identifiers
119020-03-0 - Physico-chemical Properties
| Molecular Formula | C13H18N2O2 |
| Molar Mass | 234.29 |
| Density | 1.155±0.06 g/cm3(Predicted) |
| Boling Point | 370.5±25.0 °C(Predicted) |
| Flash Point | 177.9°C |
| Vapor Presure | 1.1E-05mmHg at 25°C |
| pKa | 9.91±0.29(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,2-8°C |
| Refractive Index | 1.56 |
119020-03-0 - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R41 - Risk of serious damage to eyes R37/38 - Irritating to respiratory system and skin. R22 - Harmful if swallowed |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S39 - Wear eye / face protection. |
119020-03-0 - Introduction
(S)-2-Aminomethyl-1-Cbz-pyrrolidine, also known as (S)-2-(aminomethyl)-1-methoxycarbonylphenylpyrrolidine, is an organic compound. The following is a description of its nature, use, formulation and safety information:
Nature:
(S)-2-Aminomethyl-1-Cbz-pyrrolidine is a white to pale yellow solid that can exist as crystals. It has a high melting and boiling point and is soluble in many common organic solvents such as dichloromethane and methanol.
Use:
(S)-2-Aminomethyl-1-Cbz-pyrrolidine is an important organic intermediate used in the synthesis of other compounds. It can be used as a starting material for the preparation of biologically active compounds, medicaments or pesticides. In addition, it can also be applied to asymmetric catalytic reactions in organic synthesis and can be used as a chiral reagent for stereoselective synthesis.
Preparation Method:
(S)-2-Aminomethyl-1-Cbz-pyrrolidine is usually prepared by chemical synthesis methods. The specific method includes reacting pyrrolidine with p-toluenesulfonyl chloride to obtain pyrrolidine carbonyl chloride, and then preparing (S)-2-aminomethyl-1-Cbz-pyrrolidine by acting on ammonia gas.
Safety Information:
When using (S)-2-Aminomethyl-1-Cbz-pyrrolidine, follow appropriate laboratory safety procedures. Because it is a chemical, care should be taken to avoid inhalation, ingestion, or contact with the skin and eyes. Personal protective equipment, including laboratory gloves, goggles and protective clothing, should be used during operation. When handling or disposing of (S)-2-aminomethyl-1-Cbz-pyrrolidine, comply with local environmental regulations and follow the instructions given in the relevant safety data sheet.
Nature:
(S)-2-Aminomethyl-1-Cbz-pyrrolidine is a white to pale yellow solid that can exist as crystals. It has a high melting and boiling point and is soluble in many common organic solvents such as dichloromethane and methanol.
Use:
(S)-2-Aminomethyl-1-Cbz-pyrrolidine is an important organic intermediate used in the synthesis of other compounds. It can be used as a starting material for the preparation of biologically active compounds, medicaments or pesticides. In addition, it can also be applied to asymmetric catalytic reactions in organic synthesis and can be used as a chiral reagent for stereoselective synthesis.
Preparation Method:
(S)-2-Aminomethyl-1-Cbz-pyrrolidine is usually prepared by chemical synthesis methods. The specific method includes reacting pyrrolidine with p-toluenesulfonyl chloride to obtain pyrrolidine carbonyl chloride, and then preparing (S)-2-aminomethyl-1-Cbz-pyrrolidine by acting on ammonia gas.
Safety Information:
When using (S)-2-Aminomethyl-1-Cbz-pyrrolidine, follow appropriate laboratory safety procedures. Because it is a chemical, care should be taken to avoid inhalation, ingestion, or contact with the skin and eyes. Personal protective equipment, including laboratory gloves, goggles and protective clothing, should be used during operation. When handling or disposing of (S)-2-aminomethyl-1-Cbz-pyrrolidine, comply with local environmental regulations and follow the instructions given in the relevant safety data sheet.
Last Update：2024-04-09 21:04:16
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