1191429-20-5
(R)-N-Fmoc-2-(7'-octenyl)glycine
CAS: 1191429-20-5
Molecular Formula: C25H29NO4
1191429-20-5 - Names and Identifiers
1191429-20-5 - Physico-chemical Properties
| Molecular Formula | C25H29NO4 |
| Molar Mass | 407.5 |
| Density | 1.153±0.06 g/cm3(Predicted) |
| Boling Point | 583.8±45.0 °C(Predicted) |
| pKa | 3.91±0.21(Predicted) |
| Storage Condition | 2-8°C |
1191429-20-5 - Introduction
(R)-N-fluorenylmethoxycarbonyl-2-(7 '-octenyl) glycine, abbreviated as FMOC-Lys(Alloc)-OH, is an amino acid compound. The following is an introduction to its nature, use, preparation and safety information:
Nature:
-Appearance: White crystalline powder
-Molecular formula: C35H40N2O6
-Molecular Weight: 580.71
-melting point: 165-170 ℃
-Solubility: Soluble in organic solvents such as dimethyl sulfoxide, dimethylformamide, slightly soluble in water
Use:
- FMOC-Lys(Alloc)-OH is widely used in peptide synthesis in solid phase synthesis
-It can be used as a protecting group in the peptide synthesis process to protect the amino group in the peptide chain to prevent them from accidental reactions under the reaction conditions
-This protecting group can be easily removed by hydrolysis of the carbon-nitrogen bond, thereby providing exposed amino groups for subsequent peptide synthesis reactions
Preparation Method:
-The preparation of FMOC-Lys(Alloc)-OH generally involves multiple steps of chemical synthesis, including the use of fluorenecyl chloride and N-fluorenecyloxycarbonyl-2-chloro dehydrogenation D-glycinone to synthesize the precursor, and then through a series of reaction steps (such as amidation, carboxylic acid activation, etc.) to prepare the target product
Safety Information:
- FMOC-Lys(Alloc)-OH is a chemical, please pay attention to safe operation
-Avoid inhaling dust, avoid contact with skin and eyes, and avoid ingestion
-Use appropriate protective equipment such as chemical protective gloves and goggles
-Operate in a well-ventilated place and avoid contact with combustibles, oxidants and other substances
-If you accidentally touch or eat, you should see a doctor or consult a professional immediately
Nature:
-Appearance: White crystalline powder
-Molecular formula: C35H40N2O6
-Molecular Weight: 580.71
-melting point: 165-170 ℃
-Solubility: Soluble in organic solvents such as dimethyl sulfoxide, dimethylformamide, slightly soluble in water
Use:
- FMOC-Lys(Alloc)-OH is widely used in peptide synthesis in solid phase synthesis
-It can be used as a protecting group in the peptide synthesis process to protect the amino group in the peptide chain to prevent them from accidental reactions under the reaction conditions
-This protecting group can be easily removed by hydrolysis of the carbon-nitrogen bond, thereby providing exposed amino groups for subsequent peptide synthesis reactions
Preparation Method:
-The preparation of FMOC-Lys(Alloc)-OH generally involves multiple steps of chemical synthesis, including the use of fluorenecyl chloride and N-fluorenecyloxycarbonyl-2-chloro dehydrogenation D-glycinone to synthesize the precursor, and then through a series of reaction steps (such as amidation, carboxylic acid activation, etc.) to prepare the target product
Safety Information:
- FMOC-Lys(Alloc)-OH is a chemical, please pay attention to safe operation
-Avoid inhaling dust, avoid contact with skin and eyes, and avoid ingestion
-Use appropriate protective equipment such as chemical protective gloves and goggles
-Operate in a well-ventilated place and avoid contact with combustibles, oxidants and other substances
-If you accidentally touch or eat, you should see a doctor or consult a professional immediately
Last Update：2024-04-10 22:29:15
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