12001-79-5
Vitamin K
CAS: 12001-79-5
Molecular Formula: C31H46O2
12001-79-5 - Names and Identifiers
| Name | Vitamin K |
| Synonyms | C01628 Kanavit Vitamin K VITAMIN K Synkavite Mephyton Konakion Synkavite vitamine K Aqua-mephyton VITAMIN K1 USP23 Vitamin K substances 2-methyl-3-(3,7,11,15-tetramethylhexadec-2-en-1-yl)naphthalene-1,4-dione 2-methyl-3-[(E)-3,7,11,15-tetramethylhexadec-2-enyl]naphthalene-1,4-dione 2-methyl-3-[(2E)-3,7,11,15-tetramethylhexadec-2-en-1-yl]naphthalene-1,4-dione |
| CAS | 12001-79-5 |
| EINECS | 234-408-7 |
| InChI | InChI=1/C31H46O2/c1-22(2)12-9-13-23(3)14-10-15-24(4)16-11-17-25(5)20-21-27-26(6)30(32)28-18-7-8-19-29(28)31(27)33/h7-8,18-20,22-24H,9-17,21H2,1-6H3/b25-20+ |
12001-79-5 - Physico-chemical Properties
| Molecular Formula | C31H46O2 |
| Molar Mass | 450.7 |
| Density | 0.984g/mLat 25°C(lit.) |
| Melting Point | −20°C(lit.) |
| Boling Point | 546.4°C at 760 mmHg |
| Flash Point | >230°F |
| Vapor Presure | 5.37E-12mmHg at 25°C |
| Appearance | viscous liquid |
| Storage Condition | 2-8°C |
| Refractive Index | n20/D 1.527(lit.) |
| Physical and Chemical Properties | . White or yellowish crystalline powder. Odorless or slightly malodorous with acetic acid. Melting point 112-114 °c. Insoluble in water. Slightly soluble in ice ethanol. Soluble in boiling ethanol. |
| Use | This product is a hemostatic drug. For prothrombin too low disease, vitamin K deficiency, the prevention and treatment of neonatal natural hemorrhagic disease, due to the service of dicoumarin, salicylic acid and other excessive caused by bleeding. It is effective for angina caused by biliary Ascaris lumbricoides and the like. Side effects for oral often cause Nausea, Vomit and other gastrointestinal reactions. |
| In vitro study | Phylloquinone (vitamin K1) and Menaquinones (vitamin K2) are the two naturally occurring forms of vitamin K. Phylloquionone is the major dietary source of vitamin K and is found at highest concentrations in green leafy vegetables. Vitamin K2 (menaquinone) is found in small amounts in chicken, butter, egg yolks, cheese and fermented soyabeans. Vitamin K1 and vitamin K2 are required for the γ-glutamyl carboxylation of all vitamin K-dependent proteins. Vitamin K has important actions in the nervous system. Vitamin K contributes to the biological activation of proteins Gas6 and protein S, ligands for the receptor tyrosine kinases of the TAM family (Tyro3, Axl, and Mer). In brain, vitamin K also participates in the synthesis of sphingolipids, an important class of lipids present in high concentrations in brain cell membranes. |
| In vivo study | Vitamin K is well-known for its function in blood coagulation. Several human studies report the beneficial role of vitamin K supplementation in improving insulin sensitivity and glucose tolerance, preventing insulin resistance, and reducing the risk of type 2 diabetes. The adequate intake for vitamin K has been proposed to be 90 µg/day for women and 120 µg/day for men. Vitamin K deficiency results in an increase in undercarboxylated osteocalcin, a protein with low biological activity. Several studies have demonstrated that low dietary vitamin K intake is associated with low bone mineral density or increased fractures. Additionally, vitamin K supplementation has been shown to reduce undercarboxylated osteocalcin and improve the bone turnover profile. |
12001-79-5 - Risk and Safety
| WGK Germany | 2 |
| RTECS | QJ5800000 |
| FLUKA BRAND F CODES | 1-8-10 |
12001-79-5 - Upstream Downstream Industry
| Raw Materials | 2-Methyl-1,4-naphthoquinone |
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Mobile: 18916960931
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Tel: +86-400-900-4166
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Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
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Raw Materials for 12001-79-5