1204-44-0
4'-Chloro-Biphenyl-2-Ylamine
CAS: 1204-44-0
Molecular Formula: C12H10ClN
1204-44-0 - Names and Identifiers
1204-44-0 - Physico-chemical Properties
| Molecular Formula | C12H10ClN |
| Molar Mass | 203.67 |
| Density | 1.205±0.06 g/cm3(Predicted) |
| Melting Point | 45.0 to 49.0 °C |
| Boling Point | 334.6±17.0 °C(Predicted) |
| Flash Point | 156.163°C |
| Solubility | Chloroform (Slightly), Methanol (Slightly) |
| Vapor Presure | 0mmHg at 25°C |
| Appearance | Solid |
| Color | Off-White to Pale Beige |
| pKa | 3.26±0.10(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
| Refractive Index | 1.628 |
1204-44-0 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| Hazard Note | Irritant |
1204-44-0 - Introduction
4 '-Chloro-2-aminobiphenyl is an organic compound with a chemical formula of C12H10ClN and a structure containing a benzene ring and an amino group. Its main properties are as follows:
1. Appearance: 4 '-chloro -2-aminobiphenyl is a colorless or light yellow solid.
2. solubility: it can be dissolved in organic solvents, such as ethanol, chloroform, etc., but almost insoluble in water.
3. Melting point: Its melting point is about 100-102 degrees Celsius.
4. Chemical reaction: 4 '-chloro -2-aminobiphenyl is an aromatic amine compound with electrophilic property. It can participate in amino substitution reactions and aromatic electrophilic substitution reactions.
In practical applications, 4 '-chloro-2-aminobiphenyl has some important uses:
1. Synthesis of fluorescent dyes: It can be used as a raw material for the synthesis of fluorescent dyes for labeling biological molecules or the preparation of luminescent materials in the fields of material science.
2. drug synthesis: 4 '-chloro -2-amino biphenyl in the field of medicine for the synthesis of specific drugs, such as acetaminophen, anticancer drugs.
3. Polymer materials: It is also commonly used in synthetic polymers and polymer materials to improve the performance of materials.
The preparation method of 4 '-chloro-2-aminobiphenyl is usually achieved by aromatic electrophilic substitution reaction, for example, p-aminobenzene is reacted with chlorinated alkane to obtain the product.
When using 4 '-chloro-2-aminobiphenyl, the following safety information should be noted:
1. contact: avoid skin contact and inhalation of dust or gas. The skin should be rinsed with plenty of water immediately after contact. If splashed into eyes, rinse immediately with plenty of flowing water for at least 15 minutes and seek medical help.
2 inhalation: should maintain a well-ventilated working environment, avoid inhalation of dust or gas. If accidentally inhaled, should be quickly transferred to fresh air, such as discomfort, medical treatment.
1. Appearance: 4 '-chloro -2-aminobiphenyl is a colorless or light yellow solid.
2. solubility: it can be dissolved in organic solvents, such as ethanol, chloroform, etc., but almost insoluble in water.
3. Melting point: Its melting point is about 100-102 degrees Celsius.
4. Chemical reaction: 4 '-chloro -2-aminobiphenyl is an aromatic amine compound with electrophilic property. It can participate in amino substitution reactions and aromatic electrophilic substitution reactions.
In practical applications, 4 '-chloro-2-aminobiphenyl has some important uses:
1. Synthesis of fluorescent dyes: It can be used as a raw material for the synthesis of fluorescent dyes for labeling biological molecules or the preparation of luminescent materials in the fields of material science.
2. drug synthesis: 4 '-chloro -2-amino biphenyl in the field of medicine for the synthesis of specific drugs, such as acetaminophen, anticancer drugs.
3. Polymer materials: It is also commonly used in synthetic polymers and polymer materials to improve the performance of materials.
The preparation method of 4 '-chloro-2-aminobiphenyl is usually achieved by aromatic electrophilic substitution reaction, for example, p-aminobenzene is reacted with chlorinated alkane to obtain the product.
When using 4 '-chloro-2-aminobiphenyl, the following safety information should be noted:
1. contact: avoid skin contact and inhalation of dust or gas. The skin should be rinsed with plenty of water immediately after contact. If splashed into eyes, rinse immediately with plenty of flowing water for at least 15 minutes and seek medical help.
2 inhalation: should maintain a well-ventilated working environment, avoid inhalation of dust or gas. If accidentally inhaled, should be quickly transferred to fresh air, such as discomfort, medical treatment.
Last Update：2024-04-09 15:17:51
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