120740-10-5
C-(6-BROMO-PYRIDIN-3-YL)-METHYLAMINE
CAS: 120740-10-5
Molecular Formula: C6H7BrN2
120740-10-5 - Names and Identifiers
| Name | C-(6-BROMO-PYRIDIN-3-YL)-METHYLAMINE |
| Synonyms | 5-Aminomethyl-2-Bromopyridine 6-bromo-3-Pyridinemethanamine (6-bromo-3-pyridyl)methanamine 3-Pyridinemethanamine, 6-bromo- (6-broMopyridin-3-yl)MethanaMine (2-Bromo-5-pyridinyl)methylamine 1-(6-bromopyridin-3-yl)methanamine C-(6-BROMO-PYRIDIN-3-YL)-METHYLAMINE |
| CAS | 120740-10-5 |
| InChI | InChI=1/C6H7BrN2/c7-6-2-1-5(3-8)4-9-6/h1-2,4H,3,8H2 |
120740-10-5 - Physico-chemical Properties
| Molecular Formula | C6H7BrN2 |
| Molar Mass | 187.04 |
| Density | 1.574±0.06 g/cm3(Predicted) |
| Boling Point | 290.1±25.0 °C(Predicted) |
| Flash Point | 129.3°C |
| Vapor Presure | 0.00211mmHg at 25°C |
| pKa | 7.74±0.29(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
| Refractive Index | 1.596 |
120740-10-5 - Introduction
6-bromopyridine-3-methylamine is an organic compound with the chemical formula C6H6BrN2, in which the bromine atom is attached to carbon 6 of the pyridine ring and the methylamine group is attached to carbon 3.
Nature:
6-bromopyridine-3-methylamine is a white crystalline solid with some solubility. It can be dissolved in water and common organic solvents at room temperature.
Use:
6-bromopyridine-3-methylamine is commonly used in organic synthesis reactions, for example, as a reagent to introduce bromine atoms in chemical reactions. It also has applications in the field of medicine and can be used as a precursor or intermediate for anticancer drugs.
Method:
6-bromopyridine-3-methylamine can be obtained by reacting pyridine with bromoacetyl bromide. First, pyridine and bromoacetyl bromide are reacted under alkaline conditions to generate pyridine-3-carboxylic acid bromide, and then one bromine atom of the bromoacetyl bromide is replaced with a methylamine group by a heating reaction to obtain 6-bromopyridine-3-methylamine.
Safety Information:
Safety measures need to be taken when using and handling 6-bromopyridine-3-methylamine. It may be irritating to the eyes, skin and respiratory tract, so protective glasses, gloves and a mask should be worn during operation. Inhalation of its dust or vapors should be avoided and good ventilation should be maintained. In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical help. In addition, 6-bromopyridine-3-methylamine should be stored in a cool, dry place, away from fire and oxidizing agents.
Nature:
6-bromopyridine-3-methylamine is a white crystalline solid with some solubility. It can be dissolved in water and common organic solvents at room temperature.
Use:
6-bromopyridine-3-methylamine is commonly used in organic synthesis reactions, for example, as a reagent to introduce bromine atoms in chemical reactions. It also has applications in the field of medicine and can be used as a precursor or intermediate for anticancer drugs.
Method:
6-bromopyridine-3-methylamine can be obtained by reacting pyridine with bromoacetyl bromide. First, pyridine and bromoacetyl bromide are reacted under alkaline conditions to generate pyridine-3-carboxylic acid bromide, and then one bromine atom of the bromoacetyl bromide is replaced with a methylamine group by a heating reaction to obtain 6-bromopyridine-3-methylamine.
Safety Information:
Safety measures need to be taken when using and handling 6-bromopyridine-3-methylamine. It may be irritating to the eyes, skin and respiratory tract, so protective glasses, gloves and a mask should be worn during operation. Inhalation of its dust or vapors should be avoided and good ventilation should be maintained. In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical help. In addition, 6-bromopyridine-3-methylamine should be stored in a cool, dry place, away from fire and oxidizing agents.
Last Update：2024-04-09 21:01:54
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View History
120740-10-5
209958-42-9
64828-40-6
反应嫩黄K-6G
66607-27-0
94956-98-6
14215-97-5
61260-15-9
50606-63-8
84057-81-8
209958-42-9
64828-40-6
反应嫩黄K-6G
66607-27-0
94956-98-6
14215-97-5
61260-15-9
50606-63-8
84057-81-8