1208977-14-3
7-Fluoro-4-Trifluoromethoxy-1H-Indole
CAS: 1208977-14-3
Molecular Formula: C9H5F4NO
1208977-14-3 - Names and Identifiers
| Name | 7-Fluoro-4-Trifluoromethoxy-1H-Indole |
| Synonyms | EOS-61648 7-Fluoro-4-trifluoroMethoxy-1H-indole 7-Fluoro-4-Trifluoromethoxy-1H-Indole 1H-Indole, 7-fluoro-4-(trifluoroMethoxy)- |
| CAS | 1208977-14-3 |
1208977-14-3 - Physico-chemical Properties
| Molecular Formula | C9H5F4NO |
| Molar Mass | 219.14 |
| Density | 1.496±0.06 g/cm3(Predicted) |
| Boling Point | 263.0±35.0 °C(Predicted) |
| pKa | 14.45±0.30(Predicted) |
1208977-14-3 - Introduction
7-Fluoro-4-trifluoromethoxy-1H-indole is an organic compound with the chemical formula C8H4F4O. It is a colorless crystal with a distinctive smell.
The compound has some of the following properties:
1. Solubility: 7-fluorine -4-trifluoromethoxy -1H-indole is poorly soluble in water, but can be dissolved in organic solvents such as dimethyl sulfoxide and dimethylformamide.
2. Melting point and boiling point: 7-fluoro-4-trifluoromethoxy-1H-indole has a higher melting point and boiling point, about 190-200°C and 290-300°C, respectively.
3. Chemical properties: The compound can undergo racemization reaction in the presence of strong base, and it can also undergo substitution reaction with some compounds.
7-Fluoro-4-trifluoromethoxy-1H-indole has some applications:
1. fungicide: the compound has strong bactericidal activity, commonly used in agriculture and water treatment as a control agent.
2. Pharmaceutical field: It is often used as raw material or structural skeleton in drug research and development, and has certain pharmaceutical activity.
The compound can be prepared by the following methods:
Through a series of chemical reactions, such as aromatic substitution reaction and fluorination reaction to synthesis.
Regarding safety information, 7-fluoro-4-trifluoromethoxy-1H-indole has low toxicity, but the following matters still need to be paid attention:
1. contact: avoid skin and eye contact, such as accidental contact, should immediately rinse with water.
2. Inhalation: prolonged inhalation may cause respiratory tract irritation, so it should be operated in a well-ventilated place.
3. storage: should be stored in a dry, ventilated place, away from fire and oxidant.
When using and handling 7-fluoro-4-trifluoromethoxy-1H-indole, please follow correct working procedures and laboratory safety regulations.
The compound has some of the following properties:
1. Solubility: 7-fluorine -4-trifluoromethoxy -1H-indole is poorly soluble in water, but can be dissolved in organic solvents such as dimethyl sulfoxide and dimethylformamide.
2. Melting point and boiling point: 7-fluoro-4-trifluoromethoxy-1H-indole has a higher melting point and boiling point, about 190-200°C and 290-300°C, respectively.
3. Chemical properties: The compound can undergo racemization reaction in the presence of strong base, and it can also undergo substitution reaction with some compounds.
7-Fluoro-4-trifluoromethoxy-1H-indole has some applications:
1. fungicide: the compound has strong bactericidal activity, commonly used in agriculture and water treatment as a control agent.
2. Pharmaceutical field: It is often used as raw material or structural skeleton in drug research and development, and has certain pharmaceutical activity.
The compound can be prepared by the following methods:
Through a series of chemical reactions, such as aromatic substitution reaction and fluorination reaction to synthesis.
Regarding safety information, 7-fluoro-4-trifluoromethoxy-1H-indole has low toxicity, but the following matters still need to be paid attention:
1. contact: avoid skin and eye contact, such as accidental contact, should immediately rinse with water.
2. Inhalation: prolonged inhalation may cause respiratory tract irritation, so it should be operated in a well-ventilated place.
3. storage: should be stored in a dry, ventilated place, away from fire and oxidant.
When using and handling 7-fluoro-4-trifluoromethoxy-1H-indole, please follow correct working procedures and laboratory safety regulations.
Last Update：2024-04-09 20:44:15
