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1215387-58-8

5-Bromo-1H-pyrrolo[2,3-c]pyridine

CAS: 1215387-58-8

Molecular Formula: C7H5BrN2

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1215387-58-8 - Names and Identifiers

Name 5-Bromo-1H-pyrrolo[2,3-c]pyridine
Synonyms 5-BroMo-6-azaindole
5-Bromo-1H-pyrrolo[2,3-c]pyridine
1H-Pyrrolo[2,3-c]pyridine, 5-broMo-
CAS 1215387-58-8
EINECS 200-589-5

1215387-58-8 - Physico-chemical Properties

Molecular FormulaC7H5BrN2
Molar Mass197.03
Density1.770
Boling Point362.0±22.0 °C(Predicted)
pKa13.70±0.40(Predicted)
Storage ConditionKeep in dark place,Sealed in dry,Room Temperature

1215387-58-8 - Reference Information

application 5-bromo-1H-pyrrolo [2,3-C] pyridine is used as an intermediate in organic synthesis and pharmaceutical, mainly used in laboratory research and development process and chemical production process.
Preparation 2-(2-bromo-5-nitropyridine-4-yl)-N,N-dimethylethyl -1-Amino group is dissolved in anhydrous methanol, and a catalytic amount of glacial acetic acid is added, and 70.0 mg
(1.10 mmol) sodium cyanoborohydride is weighed in N 2 gas, mix evenly in the flask, stir and heat to
60 ℃, TLC tracks and detects the reaction progress until no reactants are found to stop the reaction, TLC detects (methanol developing agent), and the product Rf
= 0.57. The solvent of the reaction mixture is spin-dried, dissolved with dichloromethane, purified water is washed for 2
times, the organic phase is dried with anhydrous sodium sulfate, the mixture is separated by silica gel column chromatography, and the product is vacuum dried to obtain 5-bromo-1H-pyrrolo [2,3-C] pyridine.
Last Update:2024-04-09 15:16:47
1215387-58-8
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