1216815-21-2

1216815-21-2 - Names and Identifiers

Name	tert-butyl 3-(bromomethyl)-2-oxa-8-azaspiro[4.5]decane-8-carboxylate
Synonyms	8-Boc-3-broMoMethyl-2-Oxa-8-azaspiro[4.5]decane N-Boc-3-(broMoMethyl)-2-oxa-8-azaspiro[4.5]decane ert-Butyl3-(bromomethyl)-2-oxa-8-azaspiro[4.5]decane-8-carboxylate tert-butyl 3-(bromomethyl)-2-oxa-8-azaspiro[4.5]decane-8-carboxylate tert-butyl 3-(broMoMethyl)-2-oxa-8-azaspiro[4.5]decane-8-carboxylate 3-(Bromomethyl)-2-oxa-8-azaspiro[4.5]decane-8-carboxylic acid 1,1-dimethylethyl ester
CAS	1216815-21-2

1216815-21-2 - Physico-chemical Properties

Molecular Formula	C14H24BrNO3
Molar Mass	334.25
Storage Condition	Room Temprature
Sensitive	IRRITANT
MDL	MFCD11840293

1216815-21-2 - Introduction

8-Boc-3-bromomethyl-2-oxazole-8-azaspiro [4.5] decane, also known as BOC-EDAC, is an organic compound. The following is a description of its nature, use, formulation and safety information:

Nature:
-Appearance: White solid
-Melting point: about 100-104°C
-Molecular formula: C14H18BrN3O2
-Molecular weight: 345.22g/mol
-Solubility: Soluble in most organic solvents, such as dimethylformamide, dichloromethane, etc.

Use:
- BOC-EDAC are mainly used as intermediates and catalysts for organic synthesis reactions.
-It has important applications in the synthesis of peptides or drugs, especially in the activation and coupling reactions in peptide synthesis.
-It can also be used to synthesize other compounds, such as Boc-protected amides.

Preparation Method:
-The preparation of BOC-EDAC is usually carried out by the following steps:
1. First, Boc-protected amides is reacted with 3-bromomethyl-2-oxazole to generate 3-Boc-bromomethyl-2-oxazole.
2. Then, 3-Boc-bromomethyl-2-oxazole is reacted with dimethylformamide isocyanate (DIAD) under basic conditions to obtain 8-Boc-3-bromomethyl-2-oxazole-8-azaspiro [4.5] decane.

Safety Information:
- BOC-EDAC have low toxicity under normal laboratory conditions.
-Avoid contact with skin and eyes during operation, and wear protective gloves and goggles when necessary.
-Follow relevant safety practices and chemical management principles during use and storage.
-When disposing of waste, follow local regulations.

Last Update：2024-04-09 21:01:54