1228780-71-9
tert-butyl 4-((4'-chloro-5,5-diMethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)Methyl)piperazine-1-carboxylate
CAS: 1228780-71-9
Molecular Formula: C24H35ClN2O2
1228780-71-9 - Names and Identifiers
1228780-71-9 - Physico-chemical Properties
| Molecular Formula | C24H35ClN2O2 |
| Molar Mass | 419.00 |
| Density | 1.103±0.06 g/cm3(Predicted) |
| Boling Point | 493.4±45.0 °C(Predicted) |
| pKa | 7.18±0.10(Predicted) |
| Storage Condition | 2-8℃ |
1228780-71-9 - Upstream Downstream Industry
1228780-71-9 - Introduction
tert-butyl 4-((4 '-chloro-5,5-diMethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)Methyl)piperazine-1-carboxylate is an organic compound, its chemical formula is C27H36ClN3O2.
Nature:
-Appearance: White solid
-Melting point: About 80-85 degrees Celsius
-Solubility: Slightly soluble in water, soluble in organic solvents such as ethanol, ether and chloroform
-Stability: stable to light and air, and can be stored for a long time at room temperature
Use:
-As a drug intermediate: The compound is often used in the synthesis of drugs, especially as an intermediate for antipsychotics and antidepressants.
-Chemical research: It can also be used in organic synthesis reactions, such as the synthesis of catalysts and metal complexes.
Method:
tert-butyl 4-((4 '-chloro-5,5-diMethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)Methyl) the preparation of piperazine-1-carboxylate typically involves a multi-step reaction. A common preparation method is to react 4-chlorobenzyl alcohol and dimethyl sulfoxide in the presence of alkali to form 4-chlorobenzyl sulfoxide, and then react with 2, 2-Dimethyl-1-cyclohexene reacts to produce 4-(2-cyclohexenyl) methylchlorobenzene, which is then condensed with piperazine and tert-butanol to give the target product.
Safety Information:
The specific toxicity and hazard information of the compound may depend on its purity and conditions of use. In General, chemicals should be used under appropriate laboratory conditions and in accordance with local safe practices and personal protective measures.
Nature:
-Appearance: White solid
-Melting point: About 80-85 degrees Celsius
-Solubility: Slightly soluble in water, soluble in organic solvents such as ethanol, ether and chloroform
-Stability: stable to light and air, and can be stored for a long time at room temperature
Use:
-As a drug intermediate: The compound is often used in the synthesis of drugs, especially as an intermediate for antipsychotics and antidepressants.
-Chemical research: It can also be used in organic synthesis reactions, such as the synthesis of catalysts and metal complexes.
Method:
tert-butyl 4-((4 '-chloro-5,5-diMethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)Methyl) the preparation of piperazine-1-carboxylate typically involves a multi-step reaction. A common preparation method is to react 4-chlorobenzyl alcohol and dimethyl sulfoxide in the presence of alkali to form 4-chlorobenzyl sulfoxide, and then react with 2, 2-Dimethyl-1-cyclohexene reacts to produce 4-(2-cyclohexenyl) methylchlorobenzene, which is then condensed with piperazine and tert-butanol to give the target product.
Safety Information:
The specific toxicity and hazard information of the compound may depend on its purity and conditions of use. In General, chemicals should be used under appropriate laboratory conditions and in accordance with local safe practices and personal protective measures.
Last Update：2024-04-09 02:00:51
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View History
1228780-71-9
DI(TRIMETHYLOLPROPANE) TETRAACRYLATE
2380-78-1
13515-97-4
2590-16-1
2371-42-8
27144-18-9
Iguratimod
1-Phenyl-2-nitropropene
1932293-70-3
DI(TRIMETHYLOLPROPANE) TETRAACRYLATE
2380-78-1
13515-97-4
2590-16-1
2371-42-8
27144-18-9
Iguratimod
1-Phenyl-2-nitropropene
1932293-70-3
Downstream Products for 1228780-71-9
Methyl 2-[(1H-pyrrolo[2,3-b]pyridin-5-yl)oxy]-4-[4-[[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-enyl]methyl]piperazin-1-yl]benzoate
2-[(1H-pyrrolo[2,3-B]pyridin-5-yl)oxy]-4-[4-[[2-(4-chlorophenyl)-4,4-dimethyl ring Hex-1-enyl]methyl]piperazin-1-yl]benzoic acid
1-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine
2-[(1H-pyrrolo[2,3-B]pyridin-5-yl)oxy]-4-[4-[[2-(4-chlorophenyl)-4,4-dimethyl ring Hex-1-enyl]methyl]piperazin-1-yl]benzoic acid
1-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine