123148-66-3
4-Pyridinemethanol, 2-methoxy-
CAS: 123148-66-3
Molecular Formula: C7H9NO2
123148-66-3 - Names and Identifiers
123148-66-3 - Physico-chemical Properties
| Molecular Formula | C7H9NO2 |
| Molar Mass | 139.15 |
| Density | 1.155g/cm3 |
| Melting Point | 110.6℃ |
| Boling Point | 259.2°C at 760 mmHg |
| Flash Point | 110.6°C |
| Vapor Presure | 0.0067mmHg at 25°C |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Refractive Index | 1.534 |
| MDL | MFCD00859298 |
123148-66-3 - Risk and Safety
| Hazard Class | IRRITANT |
123148-66-3 - Introduction
2-Methoxy-4-pyridinemethanol is an organic compound with the chemical formula C8H11NO2.
Nature:
2-Methoxy-4-pyridinemethanol is a colorless to pale yellow liquid with a special phenolic odor. It is soluble in solvents such as water, ethanol and chloroform at room temperature.
Use:
2-Methoxy-4-pyridinemethanol is widely used in the field of drug synthesis and biochemical research. It can be used as an intermediate for antibacterial and antifungal drugs, and also as a substrate for synthetic organic synthesis and enzyme-catalyzed reactions.
Preparation Method:
The preparation of 2-methoxy-4-pyridinemethanol can be obtained by the reaction of acetylacetone and sodium p-toluenesulfonate. Specific steps are as follows:
1. Dissolve acetylacetone and sodium p-toluenesulfonate in acetonitrile.
2. Add filters and additives, heat to 80-90 degrees Celsius, and react for 16-20 hours in an inert atmosphere.
3. Filtration after cooling to give the product.
Safety Information:
2-Methoxy-4-pyridinemethanol may be irritating to the eyes, skin, and respiratory tract. Wear appropriate personal protective equipment such as chemical gloves, protective goggles and protective masks during handling and use. It should be handled in a well-ventilated area and avoid inhalation, ingestion or contact with skin. In case of accidental contact, rinse immediately with water and seek medical help.
Nature:
2-Methoxy-4-pyridinemethanol is a colorless to pale yellow liquid with a special phenolic odor. It is soluble in solvents such as water, ethanol and chloroform at room temperature.
Use:
2-Methoxy-4-pyridinemethanol is widely used in the field of drug synthesis and biochemical research. It can be used as an intermediate for antibacterial and antifungal drugs, and also as a substrate for synthetic organic synthesis and enzyme-catalyzed reactions.
Preparation Method:
The preparation of 2-methoxy-4-pyridinemethanol can be obtained by the reaction of acetylacetone and sodium p-toluenesulfonate. Specific steps are as follows:
1. Dissolve acetylacetone and sodium p-toluenesulfonate in acetonitrile.
2. Add filters and additives, heat to 80-90 degrees Celsius, and react for 16-20 hours in an inert atmosphere.
3. Filtration after cooling to give the product.
Safety Information:
2-Methoxy-4-pyridinemethanol may be irritating to the eyes, skin, and respiratory tract. Wear appropriate personal protective equipment such as chemical gloves, protective goggles and protective masks during handling and use. It should be handled in a well-ventilated area and avoid inhalation, ingestion or contact with skin. In case of accidental contact, rinse immediately with water and seek medical help.
Last Update：2024-04-09 15:17:51
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CAS: 123148-66-3
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