123536-14-1
(R)-(+)-3-aminoquinuclidine dihydro-chloride
CAS: 123536-14-1
Molecular Formula: C7H16Cl2N2
123536-14-1 - Names and Identifiers
123536-14-1 - Physico-chemical Properties
| Molecular Formula | C7H16Cl2N2 |
| Molar Mass | 199.12 |
| Density | 1.06g/cm3 |
| Melting Point | >300°C(lit.) |
| Boling Point | 165.9°C at 760 mmHg |
| Specific Rotation(α) | 24 º (c=1, H2O) |
| Flash Point | 51.1°C |
| Solubility | DMSO (Slightly, Heated, Sonicated), Methanol (Slightly, Heated, Sonicated), Wat |
| Vapor Presure | 1.83mmHg at 25°C |
| Appearance | White to Beige Powder |
| Color | White to beige |
| Storage Condition | Inert atmosphere,Room Temperature |
| Stability | Hygroscopic |
| Refractive Index | 1.551 |
| Physical and Chemical Properties | Melting point> 300°C(lit.) specific optical rotation 24 ° (c = 1, H2O) |
123536-14-1 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S38 - In case of insufficient ventilation, wear suitable respiratory equipment. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
| HS Code | 29333990 |
123536-14-1 - Introduction
R-3-aminoquinuclidine dihydrochloride is an organic compound with the chemical formula C20H24N2O2. 2HCl, also known as the dihydrochloride salt of aminoquinine. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
R-3-Aminoquinuclidine dihydrochloride is a white to pale yellow solid, soluble in water and alcoholic solvents. It is an optical isomer and is one of the active ingredients of aminoquinine.
Use:
R-3-aminoquinuclidine dihydrochloride has a wide range of applications in the pharmaceutical field. It is an important antimalarial drug that can be used to prevent and treat malaria. In addition, the compound is also used as an intermediate for sedatives and antibacterial drugs.
Preparation Method:
The preparation of R-3-aminoquinuclidine dihydrochloride is usually achieved by chemical synthesis methods. One commonly used method of preparation is the reaction of aminoquinine with hydrochloric acid to form the hydrochloride salt of R-3-aminoquinine.
Safety Information:
When handling R-3-aminoquinuclidine dihydrochloride, appropriate personal protective measures, such as wearing protective glasses and gloves, are required. Avoid direct contact with skin and inhalation of gas or dust. At the same time, it should be stored in a dry, well-ventilated place, away from fire and flammable materials. If required, waste should be disposed of in accordance with local regulations and practices.
Nature:
R-3-Aminoquinuclidine dihydrochloride is a white to pale yellow solid, soluble in water and alcoholic solvents. It is an optical isomer and is one of the active ingredients of aminoquinine.
Use:
R-3-aminoquinuclidine dihydrochloride has a wide range of applications in the pharmaceutical field. It is an important antimalarial drug that can be used to prevent and treat malaria. In addition, the compound is also used as an intermediate for sedatives and antibacterial drugs.
Preparation Method:
The preparation of R-3-aminoquinuclidine dihydrochloride is usually achieved by chemical synthesis methods. One commonly used method of preparation is the reaction of aminoquinine with hydrochloric acid to form the hydrochloride salt of R-3-aminoquinine.
Safety Information:
When handling R-3-aminoquinuclidine dihydrochloride, appropriate personal protective measures, such as wearing protective glasses and gloves, are required. Avoid direct contact with skin and inhalation of gas or dust. At the same time, it should be stored in a dry, well-ventilated place, away from fire and flammable materials. If required, waste should be disposed of in accordance with local regulations and practices.
Last Update：2024-04-09 21:11:58
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