1256387-74-2

1256387-74-2 - Names and Identifiers

Name	(1R,3S,4S)-tert-Butyl 3-(6-bromo-1H-benzo[d]imidaz ol-2-yl)-2-azabicyclo[2.2.1]heptane-2-carboxylate...
Synonyms	Ledipasvir side chain 2 Ledipasvir interMediates (1R,3S,4S)-tert-butyl 3-(6-broMo-1H-benzo[d]iMidazol-2-yl)-2-azabicyclo[2.2.1]heptane-2-carboxylate tert-butyl (1R,3S,4S)-3-(6-bromo-1H-benzo[d]imidazol-2-yl)-2-azabicyclo[2.2.1]heptane-2-carboxylate (1R,3S,4S)-tert-butyl 3-(6-broMo-1Hbenzo[d]iMidazol-2-yl)-2-azabicyclo[2,2,1] heptanes-2-carboxylate (1R,3S,4S)-tert-Butyl 3-(6-bromo-1H-benzo[d]imidaz ol-2-yl)-2-azabicyclo[2.2.1]heptane-2-carboxylate... (1R,3S,4S)-3-(6-Bromo-1Hbenzimidazol-2-yl)-2-azabicyclo[2,2,1]heptane--2-carboxylic acid-1,1-dimethylethyleste (1R,3S,4S)-3-(6-Bromo-1H-benzimidazol-2-yl)-2-azabicyclo[2.2.1]heptane-2-carboxylic acid 1,1-dimethylethyl ester 2-Azabicyclo[2.2.1]heptane-2-carboxylic acid, 3-(6-broMo-1H-benziMidazol-2-yl)-, 1,1-diMethylethyl ester,(1R,3S,4S)-
CAS	1256387-74-2
EINECS	800-428-5

1256387-74-2 - Physico-chemical Properties

Molecular Formula	C18H22BrN3O2
Molar Mass	392.29
Density	1.455±0.06 g/cm3(Predicted)
Boling Point	554.3±30.0 °C(Predicted)
pKa	10.68±0.10(Predicted)
Storage Condition	2-8°C
MDL	MFCD28386937

1256387-74-2 - Introduction

(1R,3S,4S)-tert-Butyl 3-(6-bromo-1H-benzo[d]imidaz ol-2-yl)-2-azabicyclo[2.2.1]heptane-2-carboxylate..., also known as Br-mitBCN-TBS, is an organic compound. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: Common Br-mitBCN-TBS are white or off-white solids.
-Solubility: Soluble in some organic solvents, such as ethanol, dimethyl sulfoxide and toluene.
-Melting point: According to laboratory reports, its melting point is about 60-70 ° C.

Use:
Br-mitBCN-TBS are biologically active and are mainly used in research and development in the field of medicine. It is used as an intermediate or precursor compound for the synthesis of other organic compounds, such as drugs and biomarkers. Its precise application range needs further research and exploration.

Preparation Method:
The preparation method of the Br-mitBCN-TBS can be achieved by the following reaction steps:
1. 6-bromo-1H-benzimidazole-2-amine was synthesized by appropriate synthesis method.
2. React with heptanoic anhydride to produce (1R,3S,4S)-3-(6-bromo-1h-benzimidazol-2-yl)-2-azabicyclo [2.2.1] heptane-2-carboxylic acid.
3. Finally, it reacts with tert-butanol to generate Br-mitBCN-TBS.

Safety Information:
Information regarding the safety and risks of the Br-mitBCN-TBS is insufficient. When using the compound, it is necessary to follow basic laboratory safety practices, such as wearing appropriate personal protective equipment (such as gloves and safety glasses), avoiding skin contact and inhalation, and avoiding direct ingestion. When using and handling Br-mitBCN-TBS, it should be carried out under well-ventilated laboratory conditions and comply with relevant regulations and safety guidelines. In order to accurately assess its safety and health risks, please refer to the relevant chemical databases and literature, or consult a professional.

Last Update：2024-04-09 21:54:55