1257293-79-0

1257293-79-0 - Names and Identifiers

Name	1-Boc-3-(1-hydroxy-1-methylethyl)-azetidine
Synonyms	tert-butyl 3-(2-hydroxypropan-2-yl) 1-Boc-3-(1-hydroxy-1-Methylethyl)-azetidine 1-Boc-3-(1-hydroxy-1-methylethyl)-azetidine tert-Butyl 3-(2-hydroxypropan-2-yl)azetidine-1-carboxylate tert-butyl 3-(1-Hydroxy-1-methyl-ethyl)azetidine-1-carboxylate 1-Azetidinecarboxylic acid, 3-(1-hydroxy-1-methylethyl)-, 1,1-dimethylethyl ester
CAS	1257293-79-0

1257293-79-0 - Physico-chemical Properties

Molecular Formula	C11H21NO3
Molar Mass	215.29
Storage Condition	Room Temprature

1257293-79-0 - Introduction

1-Boc-3-(1-hydroxy-1-methylethyl) azetidine is an organic compound with the chemical name tert-butoxycarbonyl-3-(1-hydroxy-1-methylethyl)-piperidine. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: Colorless or light yellow solid
-Melting point: about 60-65°C
-Molecular formula: C16H29NO3
-Molecular weight: 287.41g/mol
-Solubility: Soluble in organic solvents such as dimethyl sulfoxide, methanol and ether, slightly soluble in water.

Use:
- 1-Boc-3-(1-hydroxy-1-methylethyl) azetidine can be used as a protecting group in organic synthesis. It can protect amino or alcohol groups during organic synthesis and prevent unwanted side reactions in the reaction. After completion of the reaction, the protecting group can be removed by appropriate conditions to give the target compound.
-The compound can also be used to synthesize biologically active small molecule compounds.

Method:
- 1-Boc-3-(1-hydroxy-1-methylethyl) azetidine is generally synthesized by a two-step reaction.
1. First, acridine is reacted with 1-hydroxy -1-methyl ethanone to produce 3-(1-hydroxy -1-methyl ethyl) azetidine.
2. Next, a tert-butoxycarbonyl protecting group was introduced into the resulting product to give 1-Boc-3-(1-hydroxy-1-methylethyl) azetidine.

Safety Information:
- 1-Boc-3-(1-hydroxy-1-methylethyl) azetidine is less harmful to the human body and the environment under normal operating conditions, but it is still necessary to pay attention to its safe operation.
-Use should wear appropriate protective gloves and glasses.
-Avoid contact with skin, eyes and mucous membranes.
-Operate in a well-ventilated environment and avoid inhaling dust or steam.
-stored should be sealed, stored in a dark, dry place.

Last Update：2024-04-10 22:29:15