| Molecular Formula | C50H67N7O8 |
| Molar Mass | 894.11 |
| Density | 1.223±0.06 g/cm3(Predicted) |
| Melting Point | >177°C (dec.) |
| Boling Point | 1065.6±65.0 °C(Predicted) |
| Solubility | DMSO: ≥ 33 mg/mL |
| Appearance | Solid |
| Color | Off-White to Pale Beige |
| pKa | 10.92±0.46(Predicted) |
| Storage Condition | -20°C Freezer, Under inert atmosphere |
| In vitro study | Ombitasvir (ABT-267) is an HCV NS5A inhibitor with picomolar inhibitory potency and broad activity against various genotypes, with an EC50 range of 0.82-19.3 pM for HCV genotypes 1-5, the EC50 of genotype 6a was 366 pM. The EC50 of Ombitasvir for the subgenomic replicon of genotypes 1a-H77 and 1b-Con1 were 14.1 and 5 pM, respectively. |
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 1.118 ml | 5.592 ml | 11.184 ml |
| 5 mM | 0.224 ml | 1.118 ml | 2.237 ml |
| 10 mM | 0.112 ml | 0.559 ml | 1.118 ml |
| 5 mM | 0.022 ml | 0.112 ml | 0.224 ml |