127168-68-7
2-benzyl-5-nitro-2,3-dihydro-1H-isoindole
CAS: 127168-68-7
Molecular Formula: C15H14N2O2
127168-68-7 - Names and Identifiers
| Name | 2-benzyl-5-nitro-2,3-dihydro-1H-isoindole |
| Synonyms | LogP 2-Benzyl-5-nitroisoindoline 2-benzyl-5-nitro-2,3-dihydro-1H-isoindole 1H-isoindole, 2,3-dihydro-5-nitro-2-(phenylmethyl)- |
| CAS | 127168-68-7 |
| InChI | InChI=1/C15H14N2O2/c18-17(19)15-7-6-13-10-16(11-14(13)8-15)9-12-4-2-1-3-5-12/h1-8H,9-11H2 |
127168-68-7 - Physico-chemical Properties
| Molecular Formula | C15H14N2O2 |
| Molar Mass | 254.288 |
| Density | 1.273g/cm3 |
| Boling Point | 372.418°C at 760 mmHg |
| Flash Point | 179.032°C |
| Vapor Presure | 0mmHg at 25°C |
| Storage Condition | 2-8°C |
| Refractive Index | 1.653 |
127168-68-7 - Introduction
2-Benzyl-5-nitroisoindoline is an organic compound with the chemical formula C13H9N3O2. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 2-Benzyl-5-nitroisoindoline is a yellow solid.
-Solubility: It is soluble in organic solvents such as ethanol, dimethylformamide and dichloromethane, but hardly soluble in water.
Use:
-Pharmaceutical field: 2-benzyl-5-nitroisoindoline has anti-inflammatory and anti-tumor activities and can be used to prepare anti-cancer drugs.
-Scientific research field: It can also be used as an intermediate in organic synthesis reactions and used to synthesize other organic compounds.
Method:
2-Benzyl-5-nitroisoindoline can be prepared by the following synthetic route:
1. react 1-phenyl -1H indol-5-amine with benzyl bromide to give 2-benzyl -1-phenyl indole.
2.2-Benzyl -1-phenyl indole is reacted with nitric acid to obtain 2-benzyl -5-nitroindole.
3.2-benzyl -5-nitroindole was reacted with ethyl alkanone to obtain 2-benzyl -5-nitroisoindoline.
Safety Information:
2-Benzyl-5-nitroisoindoline is less toxic to the human body under general conditions. But as a chemical substance, still need to pay attention to the following safety precautions:
-Avoid contact with skin and eyes. If contact occurs, rinse immediately with plenty of water.
-In the operation should pay attention to the use of appropriate protective measures, such as wearing gloves and protective glasses.
-Avoid contact with combustibles during storage and handling to prevent the risk of fire and explosion.
-Follow the correct operating procedures and operate in a well-ventilated place.
-When using and disposing of compounds, follow relevant safety procedures and laws and regulations.
Nature:
-Appearance: 2-Benzyl-5-nitroisoindoline is a yellow solid.
-Solubility: It is soluble in organic solvents such as ethanol, dimethylformamide and dichloromethane, but hardly soluble in water.
Use:
-Pharmaceutical field: 2-benzyl-5-nitroisoindoline has anti-inflammatory and anti-tumor activities and can be used to prepare anti-cancer drugs.
-Scientific research field: It can also be used as an intermediate in organic synthesis reactions and used to synthesize other organic compounds.
Method:
2-Benzyl-5-nitroisoindoline can be prepared by the following synthetic route:
1. react 1-phenyl -1H indol-5-amine with benzyl bromide to give 2-benzyl -1-phenyl indole.
2.2-Benzyl -1-phenyl indole is reacted with nitric acid to obtain 2-benzyl -5-nitroindole.
3.2-benzyl -5-nitroindole was reacted with ethyl alkanone to obtain 2-benzyl -5-nitroisoindoline.
Safety Information:
2-Benzyl-5-nitroisoindoline is less toxic to the human body under general conditions. But as a chemical substance, still need to pay attention to the following safety precautions:
-Avoid contact with skin and eyes. If contact occurs, rinse immediately with plenty of water.
-In the operation should pay attention to the use of appropriate protective measures, such as wearing gloves and protective glasses.
-Avoid contact with combustibles during storage and handling to prevent the risk of fire and explosion.
-Follow the correct operating procedures and operate in a well-ventilated place.
-When using and disposing of compounds, follow relevant safety procedures and laws and regulations.
Last Update：2024-04-09 02:00:41
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Product Name: 2-Benzyl-5-nitroisoindoline Request for quotationCAS: 127168-68-7
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Product Name: 2-Benzyl-5-nitroisoindoline Visit Supplier Webpage Request for quotation
CAS: 127168-68-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 127168-68-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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