127191-86-0

Name	7-(2'-Deoxyadenosin-N6-yl)aristolactam I
Synonyms	A-Aai Aristolactam A 7-(deoxyadenosin-N(6)-yl)aristolactam I 7-(2'-Deoxyadenosin-N6-yl)aristolactam I Adenosine, 2'-deoxy-N-(5,6-dihydro-8-methoxy-5-oxobenzo[f]-1,3-benzodioxolo[6,5,4-cd]indol-7-yl)-
CAS	127191-86-0

Molecular Formula	C27H22N6O7
Molar Mass	542.5
Density	1.87±0.1 g/cm3 (20 ºC 760 Torr)
Appearance	Lens.
Storage Condition	2-8℃
Physical and Chemical Properties	Density: 1.87g/cm3; Refractive index: 1.89

chemical properties	density: 1.87g/cm3; Refractive index: 1.89
use	reference substance for identification, standard substance for content determination, active monomer
application	aristolochic lactam a, a highly active compound, can be seen to generate aristolochic lactam after oxidation, and its toxic nitro group provides binding sites for binding dna bases. Because it has strong electrophilic ability, it can bind electrophilic to the extracyclic amino group of dna base to generate corresponding adduct products, mutating ras gene and p53 gene

Last Update：2024-04-09 20:49:11

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