128595-07-3
Cyclopentyl Succinimidyl Carbonate
CAS: 128595-07-3
Molecular Formula: C10H13NO5
128595-07-3 - Names and Identifiers
128595-07-3 - Physico-chemical Properties
| Molecular Formula | C10H13NO5 |
| Molar Mass | 227.21 |
| Density | 1.35±0.1 g/cm3(Predicted) |
| Melting Point | 78.0 to 82.0 °C |
| Boling Point | 320.0±25.0 °C(Predicted) |
| Flash Point | 147.4°C |
| Vapor Presure | 0.000326mmHg at 25°C |
| Storage Condition | Inert atmosphere,2-8°C |
| Refractive Index | 1.532 |
128595-07-3 - Risk and Safety
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
128595-07-3 - Introduction
N-(cyclopentyloxycarbonyloxy) succinimide, also known as N-(cyclopentyloxycarbonyl) succinimide or N-Hydroxysuccinimide ester, is a commonly used organic compound. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
- N-(cyclopentyloxycarbonyloxy) succinimide is a white crystalline solid.
-It is easily soluble in many organic solvents at room temperature, such as dimethyl alkylene alcohol, dimethyl formamide and dimethyl imide.
-In the air, it is stable and not easy to hydrolyze.
Use:
- N-(cyclopentyloxycarbonyloxy) succinimide is an important activating reagent, which is commonly used in the preparation of amides, peptides and chemical modification of proteins.
-It can be used as a coupling reagent to mediate mixed carboxylic acids and amino compounds, linking them to form the corresponding amide bond.
-In peptide synthesis reactions, NHS esters usually react with amino acids or peptides to form temporary activated substances, which subsequently react with other amino compounds to form new amide bonds.
-In addition, N-(cyclopentyloxycarbonyloxy) succinimide also plays an important role in the research of biochemistry and medicinal chemistry.
Preparation Method:
- N-(cyclopentyloxycarbonyloxy) succinimide is prepared by a variety of methods. The most common method is to react succinic acid with N-hydroxysuccinimide.
-Specific preparation steps can refer to the chemical synthesis literature and laboratory manual.
Safety Information:
- N-(cyclopentyloxycarbonyloxy) succinimide is an irritant and should be avoided in contact with skin and eyes.
-During operation, adequate ventilation measures should be taken, such as operating under a fume hood or exhaust hood.
-Since NHS ester is a flammable solid, it should be kept away from open flames and high temperatures.
-Please refer to the relevant MSDS (Material Safety Data Sheet) and safe operating procedures when using.
Nature:
- N-(cyclopentyloxycarbonyloxy) succinimide is a white crystalline solid.
-It is easily soluble in many organic solvents at room temperature, such as dimethyl alkylene alcohol, dimethyl formamide and dimethyl imide.
-In the air, it is stable and not easy to hydrolyze.
Use:
- N-(cyclopentyloxycarbonyloxy) succinimide is an important activating reagent, which is commonly used in the preparation of amides, peptides and chemical modification of proteins.
-It can be used as a coupling reagent to mediate mixed carboxylic acids and amino compounds, linking them to form the corresponding amide bond.
-In peptide synthesis reactions, NHS esters usually react with amino acids or peptides to form temporary activated substances, which subsequently react with other amino compounds to form new amide bonds.
-In addition, N-(cyclopentyloxycarbonyloxy) succinimide also plays an important role in the research of biochemistry and medicinal chemistry.
Preparation Method:
- N-(cyclopentyloxycarbonyloxy) succinimide is prepared by a variety of methods. The most common method is to react succinic acid with N-hydroxysuccinimide.
-Specific preparation steps can refer to the chemical synthesis literature and laboratory manual.
Safety Information:
- N-(cyclopentyloxycarbonyloxy) succinimide is an irritant and should be avoided in contact with skin and eyes.
-During operation, adequate ventilation measures should be taken, such as operating under a fume hood or exhaust hood.
-Since NHS ester is a flammable solid, it should be kept away from open flames and high temperatures.
-Please refer to the relevant MSDS (Material Safety Data Sheet) and safe operating procedures when using.
Last Update：2024-04-09 21:04:16
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