130284-56-9
2-Bromo-3-chloro-5-hydroxypyridine
CAS: 130284-56-9
Molecular Formula: C5H3BrClNO
130284-56-9 - Names and Identifiers
| Name | 2-Bromo-3-chloro-5-hydroxypyridine |
| Synonyms | 6-broMo-5-chloropyridin-3-ol 6-Bromo-5-chloro-3-pyridinol 3-Pyridinol,6-broMo-5-chloro- 2-Bromo-3-chloro-5-hydroxypyridine 6-Bromo-5-chloro-3-hydroxy-pyridine |
| CAS | 130284-56-9 |
| InChI | InChI=1/C5H3BrClNO/c6-5-4(7)1-3(9)2-8-5/h1-2,9H |
130284-56-9 - Physico-chemical Properties
| Molecular Formula | C5H3BrClNO |
| Molar Mass | 208.44 |
| Density | 1.908 |
| Boling Point | 386.6±37.0 °C(Predicted) |
| pKa | 7.91±0.10(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Refractive Index | 1.629 |
130284-56-9 - Introduction
2-Bromo-3-chloro-5-hydroxypyridine is an organic compound with the chemical formula C5H3BrClNO. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: 2-Bromo-3-chloro-5-hydroxypyridine is a white to light yellow solid.
-Solubility: It has low solubility in water, but it is easier to dissolve in organic solvents.
-Chemical properties: 2-bromo-3-chloro-5-hydroxypyridine is a compound with acid-base properties, which can be reduced by a reducing agent and further reacted to generate other organic compounds.
Use:
-2-Bromo-3-chloro-5-hydroxypyridine can be used as an important intermediate in organic synthesis and used in the synthesis of other complex organic compounds.
-It can also be used as a raw material for pesticides, pharmaceuticals and dyes.
Preparation Method:
2-Bromo-3-chloro-5-hydroxypyridine can be prepared by the following steps:
1. pyridine is reacted with bromoacetic acid to generate 2-bromopyridine.
2. Further, 2-bromopyridine is reacted with aluminum trichloride to obtain 2-bromo-3-chloropyridine.
3. Finally, 2-bromo-3-chloropyridine is reacted with sodium hydroxide to produce the final product 2-bromo-3-chloro-5-hydroxypyridine.
Safety Information:
-2-Bromo-3-chloro-5-hydroxypyridine is a chemical and should be used under safe operation.
-Wear appropriate personal protective equipment, including gloves, goggles and lab coats, when in use.
-Avoid contact with skin or inhalation of particles.
-In case of contact with skin or eyes, rinse immediately with sufficient water and consult a doctor.
-Comply with relevant safety regulations for storage and disposal.
Nature:
-Appearance: 2-Bromo-3-chloro-5-hydroxypyridine is a white to light yellow solid.
-Solubility: It has low solubility in water, but it is easier to dissolve in organic solvents.
-Chemical properties: 2-bromo-3-chloro-5-hydroxypyridine is a compound with acid-base properties, which can be reduced by a reducing agent and further reacted to generate other organic compounds.
Use:
-2-Bromo-3-chloro-5-hydroxypyridine can be used as an important intermediate in organic synthesis and used in the synthesis of other complex organic compounds.
-It can also be used as a raw material for pesticides, pharmaceuticals and dyes.
Preparation Method:
2-Bromo-3-chloro-5-hydroxypyridine can be prepared by the following steps:
1. pyridine is reacted with bromoacetic acid to generate 2-bromopyridine.
2. Further, 2-bromopyridine is reacted with aluminum trichloride to obtain 2-bromo-3-chloropyridine.
3. Finally, 2-bromo-3-chloropyridine is reacted with sodium hydroxide to produce the final product 2-bromo-3-chloro-5-hydroxypyridine.
Safety Information:
-2-Bromo-3-chloro-5-hydroxypyridine is a chemical and should be used under safe operation.
-Wear appropriate personal protective equipment, including gloves, goggles and lab coats, when in use.
-Avoid contact with skin or inhalation of particles.
-In case of contact with skin or eyes, rinse immediately with sufficient water and consult a doctor.
-Comply with relevant safety regulations for storage and disposal.
Last Update：2024-04-09 21:00:56
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