131176-02-8
(2R,4S)-4-fluoropyrrolidine-2-carboxylic acid
CAS: 131176-02-8
Molecular Formula: C5H8FNO2
131176-02-8 - Names and Identifiers
131176-02-8 - Physico-chemical Properties
| Molecular Formula | C5H8FNO2 |
| Molar Mass | 133.12 |
| Density | 1.3g/cm3 |
| Boling Point | 265.1°C at 760 mmHg |
| Flash Point | 114.1°C |
| Vapor Presure | 0.00271mmHg at 25°C |
| Storage Condition | 2-8°C |
| Refractive Index | 1.472 |
131176-02-8 - Introduction
(2R,4S)-4-fluoropyrrolidine-2-carboxylic acid is an organic compound with the formula C6H7FO2, which is a white crystalline solid.
The following is a description of its nature, use, method and safety information:
Nature:
- (2R,4S)-4-fluoropyrrolidine-2-carboxylic acid has high thermal stability and solubility.
-It is stable at room temperature and not easy to decompose, but it can thermally decompose at high temperatures.
-It can be dissolved in water, alcohols and other organic solvents.
Use:
- (2R,4S)-4-fluoropyrrolidine-2-carboxylic acid can be used as an intermediate in drug synthesis, especially for the synthesis of amino acids and other organic compounds.
-It can also be used as a drug raw material in the pharmaceutical field, such as anti-epileptic drugs and anti-tumor drugs.
Preparation Method:
The preparation method of- (2R,4S)-4-fluoropyrrolidine-2-carboxylic acid is usually obtained by asymmetric synthesis. One of the common methods is to use enzyme catalysis or chiral ligands to catalyze the pseudo photosynthetic enzyme.
Safety Information:
-Due to the irritation and possible toxicity of compounds, safety measures must be taken during handling and use. Wear appropriate protective equipment such as gloves, goggles and lab coats.
-When storing and transporting, keep it away from fire and other flammable materials.
-Safety data sheets and instructions provided by the manufacturer should be strictly followed.
-When using this compound, good ventilation and reasonable operation methods should be carried out to avoid inhalation or skin contact. If the compound is accidentally inhaled or comes into contact with skin, wash it immediately and seek medical help.
The following is a description of its nature, use, method and safety information:
Nature:
- (2R,4S)-4-fluoropyrrolidine-2-carboxylic acid has high thermal stability and solubility.
-It is stable at room temperature and not easy to decompose, but it can thermally decompose at high temperatures.
-It can be dissolved in water, alcohols and other organic solvents.
Use:
- (2R,4S)-4-fluoropyrrolidine-2-carboxylic acid can be used as an intermediate in drug synthesis, especially for the synthesis of amino acids and other organic compounds.
-It can also be used as a drug raw material in the pharmaceutical field, such as anti-epileptic drugs and anti-tumor drugs.
Preparation Method:
The preparation method of- (2R,4S)-4-fluoropyrrolidine-2-carboxylic acid is usually obtained by asymmetric synthesis. One of the common methods is to use enzyme catalysis or chiral ligands to catalyze the pseudo photosynthetic enzyme.
Safety Information:
-Due to the irritation and possible toxicity of compounds, safety measures must be taken during handling and use. Wear appropriate protective equipment such as gloves, goggles and lab coats.
-When storing and transporting, keep it away from fire and other flammable materials.
-Safety data sheets and instructions provided by the manufacturer should be strictly followed.
-When using this compound, good ventilation and reasonable operation methods should be carried out to avoid inhalation or skin contact. If the compound is accidentally inhaled or comes into contact with skin, wash it immediately and seek medical help.
Last Update：2024-04-09 21:04:16
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