131766-22-8
Fmoc-D-Cys(tBu)-OH
CAS: 131766-22-8
Molecular Formula: C22H25NO4S
131766-22-8 - Names and Identifiers
131766-22-8 - Physico-chemical Properties
| Molecular Formula | C22H25NO4S |
| Molar Mass | 399.5 |
| Boling Point | 603.363℃ at 760 mmHg |
| Storage Condition | 2-8°C |
131766-22-8 - Risk and Safety
| Hazard Class | IRRITANT |
131766-22-8 - Introduction
N-Fmoc-S-tert-butyl-D-cysteine is an organic compound that is a protecting group for N-diprotic octanoyl-proline. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: White crystalline powder.
-Molecular formula: C26H33NO5S.
-Molecular weight: 471.61.
-Melting point: about 125°C.
Use:
N-Fmoc-S-tert-butyl-D-cysteine is commonly used in peptide synthesis in solid phase synthesis. It acts as a protecting group that protects the thione group of cysteine to prevent undesired reactions during synthesis. After completion of the synthesis process, the protecting group can be removed by an appropriate method.
Preparation Method:
N-Fmoc-S-tert-butyl-D-cysteine can be synthesized by reacting N-diprotic octanoyl-proline with Fmoc-Cl (fluoro-tert-butyrate-9-fluorenylcarbonyl chloride). The specific synthesis method may vary, but the reaction is usually carried out under alkaline conditions, and the target product is obtained by appropriate extraction and purification steps.
Safety Information:
- N-Fmoc-S-tert-butyl-D-cysteine is highly safe, but it is still necessary to follow laboratory safety procedures.
-Wear appropriate personal protective equipment such as lab gloves, goggles and lab coats when handling the compound.
-Avoid inhalation or contact with skin and eyes. If contact occurs, flush the affected area immediately with plenty of water and seek medical help.
-The compound may have a certain impact on the environment and should be properly handled and disposed of in accordance with local environmental regulations.
Nature:
-Appearance: White crystalline powder.
-Molecular formula: C26H33NO5S.
-Molecular weight: 471.61.
-Melting point: about 125°C.
Use:
N-Fmoc-S-tert-butyl-D-cysteine is commonly used in peptide synthesis in solid phase synthesis. It acts as a protecting group that protects the thione group of cysteine to prevent undesired reactions during synthesis. After completion of the synthesis process, the protecting group can be removed by an appropriate method.
Preparation Method:
N-Fmoc-S-tert-butyl-D-cysteine can be synthesized by reacting N-diprotic octanoyl-proline with Fmoc-Cl (fluoro-tert-butyrate-9-fluorenylcarbonyl chloride). The specific synthesis method may vary, but the reaction is usually carried out under alkaline conditions, and the target product is obtained by appropriate extraction and purification steps.
Safety Information:
- N-Fmoc-S-tert-butyl-D-cysteine is highly safe, but it is still necessary to follow laboratory safety procedures.
-Wear appropriate personal protective equipment such as lab gloves, goggles and lab coats when handling the compound.
-Avoid inhalation or contact with skin and eyes. If contact occurs, flush the affected area immediately with plenty of water and seek medical help.
-The compound may have a certain impact on the environment and should be properly handled and disposed of in accordance with local environmental regulations.
Last Update：2024-04-10 22:29:15
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