132834-58-3
1-[5-(Trifluoromethyl)pyrid-2-yl]piperazine
CAS: 132834-58-3
Molecular Formula: C10H12F3N3
132834-58-3 - Names and Identifiers
132834-58-3 - Physico-chemical Properties
| Molecular Formula | C10H12F3N3 |
| Molar Mass | 231.22 |
| Density | 1.253±0.06 g/cm3(Predicted) |
| Melting Point | 43-46°C |
| Boling Point | 122 °C (2 mmHg) |
| Flash Point | 187.921°C |
| Vapor Presure | 0mmHg at 25°C |
| Appearance | Crystalline Chunks |
| Color | Slightly yellow |
| pKa | 8.51±0.10(Predicted) |
| Storage Condition | 2-8℃ |
| Sensitive | IRRITANT |
| Refractive Index | 1.5 |
| MDL | MFCD00892750 |
132834-58-3 - Risk and Safety
| Risk Codes | R34 - Causes burns R25 - Toxic if swallowed |
| Safety Description | S37/39 - Wear suitable gloves and eye/face protection S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| HS Code | 29335990 |
| Hazard Note | Irritant |
132834-58-3 - Introduction
1-[5-(Trifluoromethyl)-2-pyridyl] piperazine is an organic compound with the chemical formula C14H10F3N3. The following is a description of its nature, use, formulation and safety information:
Nature:
1-[5-(Trifluoromethyl)-2-pyridyl] piperazine is a solid compound which is soluble in organic solvents such as chloroform, dichloromethane and methanol. It has high thermal and chemical stability.
Use:
The compound has potential application value in the field of medicine. It is studied for the development of anti-tumor, anti-inflammatory and antiviral drugs. In addition, it may also have anxiolytic and antidepressant potential.
Preparation Method:
1-[5-(Trifluoromethyl)-2-pyridyl] piperazine can be synthesized by a variety of methods. A common method is to react 1,2-cyclohexanedione and 3-amino-5-trifluoromethylpyridine to obtain an intermediate, and then proceed to the construction of the piperazine ring by further reaction.
Safety Information:
The toxicity and risks of 1-[5-(trifluoromethyl)-2-pyridyl] piperazine have not been fully studied. Appropriate personal protective measures, such as gloves, goggles, and lab coats, should be taken when using or handling this compound. In addition, the operation should be carried out in a well-ventilated area and avoid contact with the skin and inhalation. Before use, the relevant safety data sheets and operating instructions should be studied and followed in detail. If ingested or exposed to the compound by mistake, seek medical help immediately.
Nature:
1-[5-(Trifluoromethyl)-2-pyridyl] piperazine is a solid compound which is soluble in organic solvents such as chloroform, dichloromethane and methanol. It has high thermal and chemical stability.
Use:
The compound has potential application value in the field of medicine. It is studied for the development of anti-tumor, anti-inflammatory and antiviral drugs. In addition, it may also have anxiolytic and antidepressant potential.
Preparation Method:
1-[5-(Trifluoromethyl)-2-pyridyl] piperazine can be synthesized by a variety of methods. A common method is to react 1,2-cyclohexanedione and 3-amino-5-trifluoromethylpyridine to obtain an intermediate, and then proceed to the construction of the piperazine ring by further reaction.
Safety Information:
The toxicity and risks of 1-[5-(trifluoromethyl)-2-pyridyl] piperazine have not been fully studied. Appropriate personal protective measures, such as gloves, goggles, and lab coats, should be taken when using or handling this compound. In addition, the operation should be carried out in a well-ventilated area and avoid contact with the skin and inhalation. Before use, the relevant safety data sheets and operating instructions should be studied and followed in detail. If ingested or exposed to the compound by mistake, seek medical help immediately.
Last Update：2024-04-09 20:52:54
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Product Name: 1-(5-(Trifluoromethyl)pyridin-2-yl)piperazine Visit Supplier Webpage Request for quotationCAS: 132834-58-3
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CAS: 132834-58-3
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