135884-31-0
1-tert-Butoxycarbonyl-2-pyrrolylboronic acid
CAS: 135884-31-0
Molecular Formula: C9H14BNO4
135884-31-0 - Names and Identifiers
135884-31-0 - Physico-chemical Properties
| Molecular Formula | C9H14BNO4 |
| Molar Mass | 211.02 |
| Density | 1.13±0.1 g/cm3(Predicted) |
| Melting Point | 93-98 °C (dec.) (lit.) |
| Boling Point | 361.4±52.0 °C(Predicted) |
| Flash Point | 172.4°C |
| Solubility | Chloroform, Ethyl Acetate |
| Vapor Presure | 7.46E-06mmHg at 25°C |
| Appearance | Solid |
| Color | gray solid |
| BRN | 7993875 |
| pKa | 8.47±0.53(Predicted) |
| Storage Condition | -20°C |
| Refractive Index | 1.494 |
| MDL | MFCD01318939 |
135884-31-0 - Risk and Safety
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. |
| Safety Description | S37/39 - Wear suitable gloves and eye/face protection S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 10-21 |
| TSCA | No |
| HS Code | 29339900 |
| Hazard Note | Irritant |
| Hazard Class | KEEP COLD |
135884-31-0 - Reference Information
| introduction | 1-Boc-pyrrole -2-boric acid looks beige-light brown powder at room temperature and pressure, belonging to heterocyclic aromatic compounds, which can be used as intermediates in organic synthesis. 1-Boc-pyrrole-2-boric acid is a commercial organic synthon, which is used in common organic solvents such as dimethyl sulfoxide, N,N-dimethylformamide, ethyl acetate, dichloromethane The solubility is better, but the solubility in water is poor. |
| Uses | 1-Boc-pyrrole-2-boric acid is a common organic synthon, the main purpose is to participate in chiral drug molecules as a molecular skeleton And in the synthesis of biologically active molecules. Boric acid on the pyrrole ring can participate in Suzuki coupling, and a series of aryl, alkyl groups are attached to the second position of pyrrole. In addition, boric acid can also be oxidized to become hydroxyl groups under the oxidation of nitrogen oxides, and finally 2-oxo-2, 5-dihydro-pyrrole-1-carboxylic acid is obtained after tautomerization. Butyl ester. |
| Synthesis method | For the synthesis of 1-Boc-pyrrole -2-boric acid, the conventional synthesis method is to start from the pyrrole protected by Boc, the precursor of its hydroxyl group, and remove the hydrogen of the carbon atom at position 2 under the action of an appropriate strong base (such as LDA) to obtain the corresponding organolithium reagent, and then add trimethyl borate, finally, it can be obtained by hydrolysis. It should be noted that the hydrogen extraction process needs to be carried out at ultra-low temperature, generally requiring -78 ℃. |
Last Update：2024-04-09 02:00:06
Supplier List
Featured ProductsSpot supply
Product Name: N-Boc-2-pyrroleboronic acid Visit Supplier Webpage Request for quotationCAS: 135884-31-0
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Multiple SpecificationsSpot supply
Product Name: N-Boc-2-Pyrroleboronic acid Request for quotationCAS: 135884-31-0
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: N-Boc-2-pyrroleboronic acid Visit Supplier Webpage Request for quotationCAS: 135884-31-0
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: N-Boc-2-pyrroleboronic acid Visit Supplier Webpage Request for quotationCAS: 135884-31-0
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: N-Boc-2-pyrroleboronic acid Visit Supplier Webpage Request for quotationCAS: 135884-31-0
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Product Name: N-Boc-2-pyrroleboronic acid Visit Supplier Webpage Request for quotation
CAS: 135884-31-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 135884-31-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Featured ProductsSpot supply
Product Name: N-Boc-2-pyrroleboronic acid Visit Supplier Webpage Request for quotationCAS: 135884-31-0
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Multiple SpecificationsSpot supply
Product Name: N-Boc-2-Pyrroleboronic acid Request for quotationCAS: 135884-31-0
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: N-Boc-2-pyrroleboronic acid Visit Supplier Webpage Request for quotationCAS: 135884-31-0
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: N-Boc-2-pyrroleboronic acid Visit Supplier Webpage Request for quotationCAS: 135884-31-0
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: N-Boc-2-pyrroleboronic acid Visit Supplier Webpage Request for quotationCAS: 135884-31-0
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Product Name: N-Boc-2-pyrroleboronic acid Visit Supplier Webpage Request for quotation
CAS: 135884-31-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 135884-31-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
View History
135884-31-0
1042-81-5
1207840-36-5
310-93-0
26305-75-9
C.I. Direct Yellow 27, disodium salt (8CI)
4021-07-2
22280-56-4
405-79-8
1,3-DIOXOLANE
1042-81-5
1207840-36-5
310-93-0
26305-75-9
C.I. Direct Yellow 27, disodium salt (8CI)
4021-07-2
22280-56-4
405-79-8
1,3-DIOXOLANE