13734-40-2
boc-O-tert-butyl-L-threonine
CAS: 13734-40-2
Molecular Formula: C13H25NO5
13734-40-2 - Names and Identifiers
| Name | boc-O-tert-butyl-L-threonine |
| Synonyms | BOC-THR(BUT)-OH Boc-Thr(tBu)-OH Boc-Thr(But)-OH BOC-L-THR(TBU)-OH BOC-THREONINE(TBU)-OH BOC-O-T-BUTYL-L-THREONINE BOC-O-TERT-BUTYL-L-THREONINE boc-O-tert-butyl-L-threonine Boc-O-tert-butyl-L-threonine N-T-boc-O-T-butyl-L-threonine N-ALPHA-T-BOC-O-T-BUTYL-L-THREONINE N-ALPHA-T-BUTOXYCARBONYL-O-T-BUTYL-L-THREONINE N-(tert-butoxycarbonyl)-O-tert-butyl-L-threonine N-ALPHA-TERT-BUTYLOXYCARBONYL-O-TERT-BUTYL-L-THREONINE |
| CAS | 13734-40-2 |
| InChI | InChI=1/C13H25NO5/c1-8(18-12(2,3)4)9(10(15)16)14-11(17)19-13(5,6)7/h8-9H,1-7H3,(H,14,17)(H,15,16)/t8-,9+/m1/s1 |
13734-40-2 - Physico-chemical Properties
| Molecular Formula | C13H25NO5 |
| Molar Mass | 275.34 |
| Density | 1.070±0.06 g/cm3(Predicted) |
| Melting Point | 95-98°C |
| Boling Point | 391.3±37.0 °C(Predicted) |
| Flash Point | 190.4°C |
| Solubility | Soluble in DMF. |
| Vapor Presure | 3.27E-07mmHg at 25°C |
| Appearance | White powder or crystal |
| BRN | 4454820 |
| pKa | 3.53±0.10(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.462 |
| MDL | MFCD00151115 |
13734-40-2 - Risk and Safety
| WGK Germany | 3 |
| HS Code | 2924 19 00 |
13734-40-2 - Introduction
N-tert-Butoxycarbonyl-O-tert-butyl-L-threonine, also known as N-Boc-O-tBu-L-serine, is an organic compound. Its molecular formula is C15H29NO6 and its structure contains the L-isomer of threonine.
N-tert-Butoxycarbonyl-O-tert-butyl-L-threonine is generally a white crystalline solid. It has good solubility, soluble in many organic solvents, such as methanol, ethanol, dimethylformamide and so on.
For the application of N-tert-butoxycarbonyl-O-tert-butyl-L-threonine, it is often used as a protecting group in organic synthesis. With the tert-butoxycarbonyl and tert-butyl protecting groups, the protected hydroxyl group can be protected during the synthesis to prevent further reactions. The use of protecting groups is very important in the synthesis of polypeptide or drug molecules.
The method for preparing N-tert-butoxycarbonyl-O-tert-butyl-L-threonine is generally obtained by reacting threonine with tert-butyryl chloride, and then reacting with tert-butyl sodium hydroxide to generate the target product. Specific procedures can refer to organic synthesis literature and laboratory manuals.
N-tert-Butoxycarbonyl-O-tert-butyl-L-threonine is generally a white crystalline solid. It has good solubility, soluble in many organic solvents, such as methanol, ethanol, dimethylformamide and so on.
For the application of N-tert-butoxycarbonyl-O-tert-butyl-L-threonine, it is often used as a protecting group in organic synthesis. With the tert-butoxycarbonyl and tert-butyl protecting groups, the protected hydroxyl group can be protected during the synthesis to prevent further reactions. The use of protecting groups is very important in the synthesis of polypeptide or drug molecules.
The method for preparing N-tert-butoxycarbonyl-O-tert-butyl-L-threonine is generally obtained by reacting threonine with tert-butyryl chloride, and then reacting with tert-butyl sodium hydroxide to generate the target product. Specific procedures can refer to organic synthesis literature and laboratory manuals.
Last Update：2024-04-09 21:04:16
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View History
13734-40-2
1074-99-3
60658-41-5
198545-76-5
c.i. 21095
FEMA 2870
AFB STAIN
PRIMAQUINEPHOSPHATE,USP
3-DIETHYLAMINO-1-PROPYLAMINE FOR SYNTHES
Barium molybdate
1074-99-3
60658-41-5
198545-76-5
c.i. 21095
FEMA 2870
AFB STAIN
PRIMAQUINEPHOSPHATE,USP
3-DIETHYLAMINO-1-PROPYLAMINE FOR SYNTHES
Barium molybdate