13803-65-1
Anhydrotetracycline hydrochloride
CAS: 13803-65-1;101812-44-6
Molecular Formula: C22H23ClN2O7
13803-65-1 - Names and Identifiers
13803-65-1 - Physico-chemical Properties
| Molecular Formula | C22H23ClN2O7 |
| Molar Mass | 462.88 |
| Melting Point | 223 °C |
| Boling Point | 618.6°C at 760 mmHg |
| Flash Point | 327.9°C |
| Water Solubility | 5-10 g/100 mL at 20℃ |
| Solubility | Soluble in ethanol, DMSO, or DMF |
| Vapor Presure | 3.66E-16mmHg at 25°C |
| Appearance | Powder |
| Color | Yellow to bright yellow |
| BRN | 4228856 |
| Storage Condition | Refrigerator |
| Stability | Hygroscopic |
| Sensitive | Moisture Sensitive |
| MDL | MFCD00151453 |
| In vitro study | Anhydrotetracycline hydrochloride inhibits Tet(50) (IC 50 =210 μM),Tet(X) (IC 50 =41 μM), Tet(X)_3 (IC 50 =3 μM) degradations of tetracyclines. Anhydrotetracycline hydrochloride inhibits Tet(50) (IC 50 =210 μM),Tet(X) (IC 50 =75 μM), Tet(X)_3 (IC 50 =26 μM) degradations of chlortetracycline. Anhydrotetracycline hydrochloride inhibits Tet(50) (IC 50 =120 μM),Tet(X) (IC 50 =41 μM), Tet(X)_3 (IC 50 =7 μM) degradations of demeclocycline. Anhydrotetracycline hydrochloride inhibits Tet(50) (IC 50 =210 μM),Tet(X) (IC 50 =41 μM), Tet(X)_3 (IC 50 =3 μM) degradations of tetracyclines. Anhydrotetracycline hydrochloride inhibits Tet(50) (IC 50 =210 μM),Tet(X) (IC 50 =75 μM), Tet(X)_3 (IC 50 =26 μM) degradations of chlortetracycline. Anhydrotetracycline hydrochloride inhibits Tet(50) (IC 50 =120 μM),Tet(X) (IC 50 =41 μM), Tet(X)_3 (IC 50 =7 μM) degradations of demeclocycline. |
13803-65-1 - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R63 - Possible risk of harm to the unborn child R36 - Irritating to the eyes |
| Safety Description | S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| WGK Germany | 3 |
| RTECS | QI7860000 |
| HS Code | 29413020 |
13803-65-1 - Reference Information
| EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
| biological activity | Anhydrotetracycline hydrochloride is a biosynthetic precursor of tetracycline and an effective and competitive tetracycline destroying enzyme (tetracycline destructase enzymes) broad-spectrum inhibitor. Anhydrotetracycline hydrochloride are effectors of tetracycline-controlled gene expression systems in eukaryotic cells. |
Last Update：2024-04-09 20:52:54
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CAS: 13803-65-1
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View History
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