1394854-52-4
GSK-J2
CAS: 1394854-52-4
Molecular Formula: C22H23N5O2
1394854-52-4 - Names and Identifiers
1394854-52-4 - Physico-chemical Properties
| Molecular Formula | C22H23N5O2 |
| Molar Mass | 389.45 |
| Solubility | DMSO: ≥ 42 mg/mL |
| Storage Condition | -20℃ |
| In vitro study | GSK-J2 is an isomer of GSK-J1, and shows poor activity towards KDM6A and KDM6B, with IC 50 of > 100 μM and 49 μM, respectively. |
1394854-52-4 - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.568 ml | 12.839 ml | 25.677 ml |
| 5 mM | 0.514 ml | 2.568 ml | 5.135 ml |
| 10 mM | 0.257 ml | 1.284 ml | 2.568 ml |
| 5 mM | 0.051 ml | 0.257 ml | 0.514 ml |
Last Update：2024-01-02 23:10:35
1394854-52-4 - Introduction
GSK-J2 is a chemical substance, which belongs to the compound in the substance class. The following is a description of the nature, use, preparation and safety information of the GSK-J2:
Nature:
The chemical structure of GSK-J2 is 4,4-dicyano -6-methyl -2H-pyranofuran -3-one. It is a white crystalline solid with a high melting point and molecular weight. It is soluble in some organic solvents, such as chloroform and dimethyl sulfoxide.
Use:
GSK-J2 is a selective disease regulator that can be used to study and treat diseases such as cancer. Its main mechanism of action is to regulate related signaling pathways through targeted inhibition of specific enzyme activities, thereby affecting cell proliferation and survival.
Preparation Method:
GSK-J2 can be obtained by chemical synthesis. The specific preparation method usually includes steps such as synthesis reaction, isolation and purification, and crystallization. Due to the complex synthesis route, the preparation of GSK-J2 requires certain knowledge and technology of chemical synthesis.
Safety Information:
When using the GSK-J2, you need to pay attention to relevant safety information. Due to the activity of GSK-J2, it may have certain toxicity and side effects on the human body. During use, relevant laboratory practices must be followed and appropriate personal protective measures must be taken, such as wearing gloves, goggles, etc. In addition, for laboratories that use GSK-J2, relevant laws and regulations should be followed, and strict laboratory safety management should be carried out.
It should be noted that the above information is general, and the specific nature, use, preparation and safety information may be affected by different sources and documents, therefore, further validation and evaluation are needed in specific applications and studies.
Nature:
The chemical structure of GSK-J2 is 4,4-dicyano -6-methyl -2H-pyranofuran -3-one. It is a white crystalline solid with a high melting point and molecular weight. It is soluble in some organic solvents, such as chloroform and dimethyl sulfoxide.
Use:
GSK-J2 is a selective disease regulator that can be used to study and treat diseases such as cancer. Its main mechanism of action is to regulate related signaling pathways through targeted inhibition of specific enzyme activities, thereby affecting cell proliferation and survival.
Preparation Method:
GSK-J2 can be obtained by chemical synthesis. The specific preparation method usually includes steps such as synthesis reaction, isolation and purification, and crystallization. Due to the complex synthesis route, the preparation of GSK-J2 requires certain knowledge and technology of chemical synthesis.
Safety Information:
When using the GSK-J2, you need to pay attention to relevant safety information. Due to the activity of GSK-J2, it may have certain toxicity and side effects on the human body. During use, relevant laboratory practices must be followed and appropriate personal protective measures must be taken, such as wearing gloves, goggles, etc. In addition, for laboratories that use GSK-J2, relevant laws and regulations should be followed, and strict laboratory safety management should be carried out.
It should be noted that the above information is general, and the specific nature, use, preparation and safety information may be affected by different sources and documents, therefore, further validation and evaluation are needed in specific applications and studies.
Last Update：2024-04-09 21:04:16
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Product Name: GSK-J2 Visit Supplier Webpage Request for quotationCAS: 1394854-52-4
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Email: Int06@meryer.com
Mobile: +86-18821248368
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Product Name: GSK-J2 Visit Supplier Webpage Request for quotationCAS: 1394854-52-4
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
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Product Name: GSK-J2 Visit Supplier Webpage Request for quotationCAS: 1394854-52-4
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Product Name: GSK-J2 Visit Supplier Webpage Request for quotation
CAS: 1394854-52-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 1394854-52-4
Tel: 18301782025
Email: 3008007409@qq.com
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