1415-73-2
aloin
CAS: 1415-73-2;5133-19-7
Molecular Formula: C21H22O9
1415-73-2 - Names and Identifiers
1415-73-2 - Physico-chemical Properties
| Molecular Formula | C21H22O9 |
| Molar Mass | 418.39 |
| Density | 1.648g/cm3 |
| Melting Point | 148-149°; monohydrate, mp 70-80° |
| Boling Point | 752.602°C at 760 mmHg |
| Specific Rotation(α) | +21°(water) |
| Flash Point | 267.997°C |
| Solubility | Soluble in pyridine, soluble in glacial acetic acid, formic acid, acetone, methyl acetate, and ethanol. |
| Vapor Presure | 0mmHg at 25°C |
| Appearance | Yellow or yellowish crystalline powder |
| Storage Condition | 2-8℃ |
| Refractive Index | 1.741 |
| MDL | MFCD00151160 |
1415-73-2 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
1415-73-2 - Reference
| Reference Show more | 1. Liu Weibin, Ge Mingjian, Ye Xiaoye, et al. Study on the Effect of Aloin Combined with Cisplatin on Non-small Cell Lung Cancer Cells [J]. Chinese Journal of Clinical Pharmacology, 2020, v.36;No.304(02):56-59. 2. Ji Huijie, Yang Yanjun, Xue Junli, et al. Study on Ultrasonic Extraction of Aloin from Aloe [J]. Heilongjiang Agricultural Sciences, 2015(2):94-98. 3. Qian Wenhui, Liu Wenya, Gong Guangming, et al. Preparation of mistletoe-Lu whitening sunscreen gel and investigation of its in vitro transdermal behavior [J]. Chinese Pharmacist, 2020, v.23(06):97-101. 4. Jiang, Kangfeng, et al. "Barbaloin protects against lipopolysaccharide (LPS)-induced acute lung injury by inhibiting the ROS-mediated PI3K/AKT/NF-κB pathway." International immunopharmacology 64 (2018): 140-150.https://doi.org/10.1016/j. insimp. 2018.08.023 5. [IF=3.361] Kangfeng Jiang et al."Barbaloin protects against lipopolysaccharide (LPS)-induced acute lung injury by inhibiting the ROS-mediated PI3K/AKT/NF-κB pathway."Int Immunopharmacol. 2018 Nov;64:140 6. [IF=4.36] Gaofeng Shi et al."Aloe vera mitigates dextran sulfate sodium-induced rat ulcerative colitis by potentiating colon mucus barrier."J Ethnopharmacol. 2021 Oct;279:114108 7. [IF=2.391] Zhang Xiao et al."Graphene oxide exhibited positive effects on the growth of Aloe vera L."Physiol Mol Biol Pla. 2021 Apr;27(4):815-824 8. [IF=4.451] Furong Wang et al.Network pharmacology combined with metabolomics to investigate the anti-hyperlipidemia mechanism of a novel combination.J Funct Foods. 2021 Dec;87:104848 9. [IF=2.552] Wang Sha et al."A newly isolated human intestinal strain deglycosylating flavonoid C- glycosides."ARCHIVES OF MICROBIOLOGY. 2022 Jun;204(6):1-8 |
1415-73-2 - Reference Information
| introduction | aloin is a natural organic compound, the English name is Aloin or Barbaloin, also known as aloin, aloe emodin, aloin, and aloin. it crystallizes in ethanol as yellow needle-like crystals. Easily soluble in water, pyridine, soluble in glacial acetic acid, formic acid, acetone, methyl acetate and ethanol. It is a concentrated dried sap of the leaves of the monocotyledonous plants, the AloebarbadensisMiller of Aloe vera, the Cape of Good Hope AloeferoxMiller, or other related plants of the same genus (such as Aloe vera). |
| efficacy and action | aloin, a kind of anthraquinone compound, that is, the yellow liquid between aloe leaf surface and aloe gel, has the effect of deworming and disinfection. In medicine, aloin has a venting effect and is used to treat constipation. Aloin has the physiological effects of purgative effect, depigmentation, tyrosinase inhibition, free radical scavenging effect and antibacterial activity. |
| application | aloin, chemical name 10-glucopyranosyl -1,8-dihydroxy -3-(hydroxymethyl)-9(10H)-anthrone. The active ingredient is a mixture of aloin, which is a dicotyledonous aloe extract. It has bactericidal and detoxifying effects on acne and acne. |
Last Update：2024-04-09 21:48:26
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