1420-04-8
Niclosamide ethanolamine salt
CAS: 1420-04-8
Molecular Formula: C15H15Cl2N3O5
1420-04-8 - Names and Identifiers
| Name | Niclosamide ethanolamine salt |
| Synonyms | BAYER73 Mollutox Luomiecide Clonitralide Bayluscid[R] niclosamide-olamine NICLOSAMIDE ETHANOLAMINE Phenasal ethanolamine salt Ethanolamine salt Niclosamide Niclosamide ethanolamine salt 2'',5-DICHLORO-4''-NITROSALICYLANILIDE(NICLOSAMIDE) 5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide 2',5-Dichloro-4'-nitrosalicylanilide 2-aminoethanol salt 5-Chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide 2-aminoethanol salt |
| CAS | 1420-04-8 |
| EINECS | 215-811-7 |
| InChI | InChI=1/C13H8Cl2N2O4.C2H7NO/c14-7-1-4-12(18)9(5-7)13(19)16-11-3-2-8(17(20)21)6-10(11)15;3-1-2-4/h1-6,18H,(H,16,19);4H,1-3H2 |
1420-04-8 - Physico-chemical Properties
| Molecular Formula | C15H15Cl2N3O5 |
| Molar Mass | 388.2 |
| Melting Point | 204° |
| Boling Point | 424.5°C at 760 mmHg |
| Flash Point | 210.5°C |
| Vapor Presure | 8.35E-08mmHg at 25°C |
| Appearance | Yellow solid |
| Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
| Stability | Stable. Hydrolyzes in concentrated acidic or basic solutions. |
| Use | Can be used for the prevention and control of Pomacea canaliculata |
1420-04-8 - Risk and Safety
| UN IDs | UN2588 (Pesticide, solid, poi-sonous, n.o.s.); UN2902 (Pesticide, liquid, poisonous,n.o.s.) |
| Toxicity | LD50 oral in rat: 500mg/kg |
1420-04-8 - Reference Information
| EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
| introduction | spiromide is a product recommended by WHO for the control of rice snails, which is friendly and safe to the environment and human beings. Spiromamide is difficult to dissolve in water. In order to improve its water solubility, it is made into spiromamide ethanolamine salt, so that the solubility in water reaches 0.1g/L (20 degrees Celsius), and it also reduces the irritation to the eyes and skin. |
| biological activity | Niclosamide olamine (BAY2353 olamine) is an insect repellent that can disrupt mitochondrial metabolism in parasites and animal models. Niclosamide olamine reversibly inhibit the mammalian target of rapamycin complex (mTORC1), thereby inhibiting STAT3 (IC50 is 0.25 μM) and stimulating autophagy (autophagy) response. |
| use | can be used to control snails, etc. |
| toxic substance data | information provided by: pubchem.ncbi.nlm.nih.gov (external link) |
Last Update：2024-04-10 22:29:15
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