1420477-60-6
Acalabrutinib
CAS: 1420477-60-6
Molecular Formula: C26H23N7O2
1420477-60-6 - Names and Identifiers
1420477-60-6 - Physico-chemical Properties
| Molecular Formula | C26H23N7O2 |
| Molar Mass | 465.507 |
| Density | 1.37±0.1 g/cm3(Predicted) |
| Melting Point | >133°C (dec.) |
| Appearance | Form solid, color Yellow |
| pKa | 11.47±0.70(Predicted) |
| Storage Condition | Refrigerator |
| Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months. |
| Use | Use ACP-196 is an experimental anticancer drug and a selective Bruton tyrosine kinase (BTK) inhibitor. This kinase transmits signals from the B- cell receptor (BCR), so any hereditary BTK mutation can cause B- cell immunodeficiency. Thus, BTK inhibitors targeting B- cell signaling have shown great promise in the treatment of chronic lymphocytic leukemia (CLL). |
1420477-60-6 - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.148 ml | 10.741 ml | 21.482 ml |
| 5 mM | 0.43 ml | 2.148 ml | 4.296 ml |
| 10 mM | 0.215 ml | 1.074 ml | 2.148 ml |
| 5 mM | 0.043 ml | 0.215 ml | 0.43 ml |
Last Update：2024-01-02 23:10:35
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