142355-83-7
tert-Butyl 4-(4-hydroxybutyl)-piperidine-1-carboxylate
CAS: 142355-83-7
Molecular Formula: C14H27NO3
142355-83-7 - Names and Identifiers
142355-83-7 - Physico-chemical Properties
| Molecular Formula | C14H27NO3 |
| Molar Mass | 257.37 |
| Density | 1.018 |
| Boling Point | 355.1±15.0 °C(Predicted) |
| pKa | 15.18±0.10(Predicted) |
| Storage Condition | 2-8°C |
| Sensitive | Irritant |
| MDL | MFCD03265708 |
142355-83-7 - Introduction
tert-Butyl 4-(4-hydroxybutyl)-piperidine-1-carboxylate is an organic compound with the chemical formula C14H29NO3. It is a white solid that can be dissolved in organic solvents.
The main use of this compound is to synthesize intermediates in organic synthesis, especially for the preparation of drugs. It is commonly used in the pharmaceutical field to synthesize biologically active molecules, such as glucocorticoid receptor agonists.
The method for preparing tert-Butyl 4-(4-hydroxybutyl)-piperidine-1-carboxylate includes two main steps. First, 4-cyano-1-butanol was obtained by structural modification of butanediol using 1-piperidinecarboxylic acid and hydrocyanic acid. Then, by reacting with tert-butyldimethylcarbamate, the target product tert-Butyl 4-(4-hydroxybutyl)-piperidine-1-carboxylate was obtained.
Regarding safety information, this compound is an organic compound that needs to be used and stored in accordance with the general safety procedures for chemicals. It may be irritating to the skin, eyes and respiratory tract, so the necessary protective measures should be taken during use, such as wearing appropriate personal protective equipment. In addition, it should be stored in a cool, dry place, away from heat sources and open flames.
The main use of this compound is to synthesize intermediates in organic synthesis, especially for the preparation of drugs. It is commonly used in the pharmaceutical field to synthesize biologically active molecules, such as glucocorticoid receptor agonists.
The method for preparing tert-Butyl 4-(4-hydroxybutyl)-piperidine-1-carboxylate includes two main steps. First, 4-cyano-1-butanol was obtained by structural modification of butanediol using 1-piperidinecarboxylic acid and hydrocyanic acid. Then, by reacting with tert-butyldimethylcarbamate, the target product tert-Butyl 4-(4-hydroxybutyl)-piperidine-1-carboxylate was obtained.
Regarding safety information, this compound is an organic compound that needs to be used and stored in accordance with the general safety procedures for chemicals. It may be irritating to the skin, eyes and respiratory tract, so the necessary protective measures should be taken during use, such as wearing appropriate personal protective equipment. In addition, it should be stored in a cool, dry place, away from heat sources and open flames.
Last Update：2024-04-09 21:01:54
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Product Name: 4-(1-Boc-4-piperidyl)-1-butanol Visit Supplier Webpage Request for quotationCAS: 142355-83-7
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